Integrated Transcriptome and Metabolome Analysis Reveals Insights into Flavone and Flavonol Biosynthesis in Salicylic Acid-Induced Huanglongbing Tolerance.

Salicylic acid (SA) exhibits positive effects against Huanglongbing (HLB), but how SA affects citrus resistance to HLB is currently unknown. This study conducted integrated transcriptome and metabolome analyses on SA-treated (HLB-sensitive) and (HLB-tolerant). The results indicated that the syntheses of flavones and flavonols were induced by SA, while the expression levels of associated genes and the contents of corresponding metabolites varied significantly between the two species after SA treatment or HLB infection.

B(OH)-Mediated Reductive Ring-Opening of -Tosyl Aziridines by Nitroarenes: A Green and Regioselective Access to Vicinal Diamines.

The nucleophilic ring-opening of aziridine derivatives provides an important synthetic tool for the preparation of various β-functionalized amines. Amines as nucleophiles are employed to prepare synthetically useful 1,2-diamines in the presence of various catalysts or activators. Herein, the B(OH)-mediated reductive ring-opening transformation of -tosyl aziridines by nitroarenes was developed.

A Synthesis of α-Alkyl Cycloenones by Pd-Catalyzed Suzuki-Miyaura Coupling with Cyclic Morita-Baylis-Hillman Adducts.

We herein disclose a Pd-catalyzed Suzuki-Miyaura coupling of cyclic Morita-Baylis-Hillman adducts with organoboronic acids under mild conditions, which allows for a rapid access to diverse α-alkyl substituted cycloenones. The advantage of this method resides in the employment of functionalized allyl alcohols as the unprecedented electrophilic partners in the absence of external activators.

Synthesis of -Methylated Benzamides via Palladium-Catalyzed Denitrogenative Cross-Coupling Reaction of [1,2,3]-Benzotriazin-4(3)-ones with DABAL-Me.

We herein developed a palladium-catalyzed reaction of [1,2,3]-benzotriazin-4(3)-ones with DABAL-Me [bis(trimethylaluminum)-1,4-diazabicyclo[2.2.2]octane adduct], a cheap, stable, and solid organoaluminum reagent.