Robust feature learning using contractive autoencoders for multi-omics clustering in cancer subtyping.

Cancer can manifest in virtually any tissue or organ, necessitating precise subtyping of cancer patients to enhance diagnosis, treatment, and prognosis. With the accumulation of vast amounts of omics data, numerous studies have focused on integrating multi-omics data for cancer subtyping using clustering techniques. However, due to the heterogeneity of different omics data, extracting important features to effectively integrate these data for accurate clustering analysis remains a significant challenge.

Transposon Mining in the Small Genomes of Animals.

TEs, including DNA transposons, are major contributors of genome expansions, and have played a very significant role in shaping the evolution of animal genomes, due to their capacity to jump from one genomic position to the other. In this study, we investigated the evolution landscapes of transposons, including their distribution, diversity, activity and structure organization in 79 species of small (compact) genomes of animals comprising both vertebrate and invertebrates. Overall, 212 transposon types were detected from almost half (37) of the total number of the small genome species (79) investigated.

Early human albumin administration is associated with reduced mortality in septic shock patients with acute respiratory distress syndrome: A retrospective study from the MIMIC-III database.

Sepsis-induced acute respiratory distress syndrome (ARDS) was associated with higher mortality. It is unclear whether albumin supplementation early in the course of ARDS can affect the prognostic outcomes of septic shock (SS) patients with ARDS. The MIMIC-III database was employed to identify SS patients with ARDS.

Phylogenetic Relationships among TnpB-Containing Mobile Elements in Six Bacterial Species.

Some families of mobile elements in bacterial genomes encode not only a transposase but also an accessory TnpB gene. This gene has been shown to encode an RNA-guided DNA endonuclease, co-evolving with Y1 transposase and serine recombinase in mobile elements and . In this paper, we reveal the evolutionary relationships among TnpB-containing mobile elements (TCMEs) in well-assembled genomes of six bacterial species: , , , , and .

The Annotation of Zebrafish Enhancer Trap Lines Generated with Transposon.

An enhancer trap (ET) mediated by a transposon is an effective method for functional gene research. Here, an ET system based on a transposon that carries a mini Krt4 promoter (the minimal promoter from zebrafish) and the gene () has been used to produce zebrafish ET lines. One enhancer trap line with eye-specific expression GFP named EYE was used to identify the trapped enhancers and genes.

Dielectric barrier discharge coupled with Fe, Mn and Cu scrubbing for toluene removal.

By-product ozone emission is one of the challenges for applying dielectric barrier discharge (DBD) technology for volatile organic compounds (VOCs) removal. In this study, a DBD reactor followed by a wet scrubber (WS) containing a solution of metal ions (Fe/Mn/Cu) was used to reuse ozone for further oxidation of typical VOC toluene. Compared with the degradation effect of the DBD reactor alone, DBD coupled WS/iron system not only improved the toluene removal efficiency but also significantly reduced the ozone emission.