Integration of multi-omics data can provide information on biomolecules from different layers to illustrate the complex biology systematically. Here, we build a multi-omics atlas containing 132,570 transcripts, 44,473 proteins, 19,970 phosphoproteins, and 12,427 acetylproteins across wheat vegetative and reproductive phases. Using this atlas, we elucidate transcriptional regulation network, contributions of post-translational modification (PTM) and transcript level to protein abundance, and biased homoeolog expression and PTM in wheat.
View Article and Find Full Text PDFUnlabelled: Flag leaf senescence is a critical factor affecting the yield and quality of wheat. The aim of this study was to identify QTLs associated with flag leaf senescence in an F recombinant inbred line population derived from durum wheats UC1113 and Kofa. Bulked segregant analysis using the wheat 660K SNP array identified 3225 SNPs between extreme-phenotype bulks, and the differential SNPs were mainly clustered on chromosomes 1A, 1B, 3B, 5A, 5B, and 7A.
View Article and Find Full Text PDFAggression among adolescents is a significant public health concern worldwide. To safeguard adolescents' physical and mental health, controlling the incidence of aggressive behavior and its triggers and drivers is necessary. Different risk factors in each environment drive adolescent aggression.
View Article and Find Full Text PDFIn this work, growth of a titanium dioxide microplug (TDMP) having mesoporous channels at the tip of a glass micropipette induced by space-confined evaporation is reported. Moreover, clear ion current rectification (ICR) of a single-material nanopore in a saturated potassium chloride solution is observed for the first time. TDMP presents an asymmetrical channel structure with the top and bottom apertures of 12.
View Article and Find Full Text PDFAs one of the most interesting naturally-occurring geometries, micro-helical structures have attracted attention due to their potential applications in fabricating biomedical and microelectronic devices. Conventional processing techniques for manufacturing micro-helices are likely to be limited in cost and mass-productivity, while , which shows natural fine micro-helical forms, can be easily mass-reproduced at an extremely low cost. Furthermore, considering the extensive utility of conducting polymers, it is intriguing to synthesize conducting polymer micro-helices.
View Article and Find Full Text PDFThe accurate treatment of tumors with the help of multimodality imaging is of great significance. Herein, a novel multifunctional probe combining active targeted fluorescent imaging (FL)/photoacoustic imaging (PA) and chemo-photothermal therapy for tumors has been designed. Targeting molecule folate (FA) modified graphene oxide (GO) was used to coat core-shell silver sulfide@mesoporous silica (QD@Si) while antitumoral doxorubicin (DOX) was loaded in mesoporous channels by electrostatic adhesion, and a delivery system (QD@Si-D/GO-FA) for active targeted dual-mode imaging and synergistic chemo-photothermal for tumors was successfully obtained.
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