Two novel diketopiperazine dimers (1 and 2) and two new 4-hydroxyphenylacetates (5 and 6), along with two previously known diketopiperazine dimers were isolated from the culture of the endolichenic fungus Aspergillus sp. CPCC 400810. Their structures were determined through comprehensive spectroscopic analysis, including high-resolution electrospray ionization mass spectrometry (HRESIMS) and 1D and 2D nuclear magnetic resonance (NMR) data.
View Article and Find Full Text PDFBackground: Autophagy plays an essential role in the occurrence and progression of necrotizing enterocolitis (NEC). We intend to carry out the identification and validation of the probable autophagy-related genes of NEC bioinformatics methods and experiment trials.
Methods: The autophagy-related differentially expressed genes (arDEGs) of NEC were identified by analyzing the RNA sequencing data of the experiment neonatal mouse model and dataset GSE46619.