Publications by authors named "Mengjia Chang"

Background: Intermediate cells are present in the early stages of human prostate development and adenocarcinoma. While primary cells isolated from benign human prostate tissues or tumors exhibit an intermediate phenotype in vitro, they cannot form tumors in vivo unless genetically modified. It is unclear about the stem cell properties and tumorigenicity of intermediate cells.

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  • Depression is a widespread issue, often treated with drugs that come with side effects; however, probiotics and goat milk, particularly Tibetan kefir, are being explored for their ability to improve mental health and immune function.
  • In experiments with mice facing chronic mild stress, Tibetan kefir significantly reduced signs of despair and inflammation, impacting the neuroendocrine system positively.
  • The findings suggest that Tibetan kefir can help restore gut microbiota and may serve as a promising dietary addition for people dealing with depression, revealing potential underlying mechanisms for its benefits.
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  • - Depression is a common psychiatric condition marked by a persistently low mood, and traditional medications often have low effectiveness and negative side effects due to unpredictable treatment responses.
  • - This study focused on selenium-enriched fermented goat milk and its effects on mice experiencing stress-induced depression, demonstrating that Se-Lactobacillus paracasei 20241 improved depressive symptoms and reduced inflammation and glucocorticoid resistance.
  • - The research also noted changes in gut bacteria diversity and oxidative stress levels in key brain and liver areas, suggesting that Se-20241 could pave the way for developing probiotic supplements to help treat depression.
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The accurate estimation of time of flight (TOF) of an ultrasonic signal is essential in ultrasonic non-destructive testing (NDT). A novel method for TOF estimation based on the short-time Fourier transform (STFT) is proposed in this paper. Firstly, the time and frequency components of ultrasonic echoes are represented by a STFT.

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