Publications by authors named "Mengistu Fereja"

There is a high incidence of neural tube defects (NTDs) in Ethiopia and folate insufficiency, a primary risk factor for NTDs, is common among Ethiopian women of reproductive age (WRA). Folic acid fortification of salt has been proposed as a strategy to control these problems. In preparation for an intervention trial to assess the nutritional effects of folic acid-fortified salt, we measured discretionary salt intakes among nonpregnant WRA using observed weighed food records, and we assessed household salt disappearance rates.

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Article Synopsis
  • Ethiopia has a high prevalence of neural tube defects (NTDs), largely due to folate insufficiency among women of reproductive age, prompting a study on fortifying iodized salt with folic acid as a potential solution.
  • The study will involve 360 non-pregnant women aged 18-49, randomly assigned to receive iodized salt fortified with either 30 ppm or 90 ppm of folic acid, or regular iodized salt, over a 26-week period to assess its acceptability and impact on nutritional status.
  • Outcomes will include monitoring women's consumption of the salts, changes in biomarker levels for folate and iodine, and any adverse events, with results analyzed to determine the effectiveness of the fortification strategy
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Background: Maternal iodine deficiency (ID) during pregnancy has been recognized as a major cause of abortion, stillbirth, congenital abnormalities, perinatal mortality and irreversible mental retardation. In Ethiopia limited information is available regarding the epidemiology of maternal ID. The purpose of the present study was to assess the prevalence of iodine deficiency and associated factors among pregnant women in Ada district, Oromia region, Ethiopia.

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