Publications by authors named "Menghao Yin"
Messenger RNA (mRNA) is an emerging class of therapeutic agents for treating a wide range of diseases. However, due to the instability and low cell transfection rate of naked mRNA, the expression of delivered mRNA in target cells or tissues in vivo requires delivery strategies. Biomimetic vectors hold advantages such as high biocompatibility, tissue specific targeting ability and efficient delivery mechanisms, potentially overcoming challenges faced by other delivery vectors.
View Article and Find Full Text PDFArticle Synopsis
- - Radiation therapy for abdominal or pelvic tumors often leads to intestinal injury, impacting patients' quality of life and prognosis, with no effective oral method for radioprotection currently available.
- - Previous research showed that nanomaterials from the spore coat of probiotics have anti-inflammatory properties and may inhibit cancer progression.
- - This study investigates the radioprotective effects of spore coats from three probiotics, demonstrating their ability to reduce radiation-induced intestinal damage, restore intestinal flora, and improve weight gain and survival in mice after radiation exposure.