Lung enteric-type adenocarcinoma with gastric metastasis: a rare case report and literature review.

Lung enteric-type adenocarcinoma (ETAC) is a rare subtype of non-small cell lung cancer (NSCLC), comprising approximately 0.6% of all primary lung adenocarcinomas. It is characterized by a tendency for early metastasis and a prognosis comparable to that of common lung adenocarcinoma.

-Semiquinone Radical and -Benzoquinone Selectively Degrade Aniline Contaminants in the Periodate-Mediated Advanced Oxidation Process.

Advanced oxidation processes (AOPs) often employ strong oxidizing inorganic radicals (e.g., hydroxyl and sulfate radicals) to oxidize contaminants in water treatment.

Molecularly imprinted polymer sheathed mesoporous silica tube as SPME fiber coating for determination of tobacco-specific nitrosamines in water.

Tobacco-specific nitrosamines (TSNAs) are probably carcinogenic disinfection byproducts eliciting health risk concerns. The determination and surveillance of TSNAs in water is still cumbersome due to the lack of advanced sample preparation methods. Herein, we prepared a solid phase microextraction (SPME) fiber coated with the molecularly imprinted polymer (MIP) sheathed mesoporous silica tube (MST) composite material, and developed a highly efficient, selective, and sensitive method for the determination of five TSNAs in water.

Complement factor H inhibits endothelial cell migration through suppression of STAT3 signaling.

Complement factor H (CFH), a major soluble inhibitor of complement, is a plasma protein that directly interacts with the endothelium of blood vessels. Mutations in the CFH gene lead to diseases associated with excessive angiogenesis; however, the underlying mechanisms are unknown. The present study aimed to determine the effects of CFH on endothelial cells and to explore the underlying mechanisms.

Synergistic cytotoxicity of binary combinations of inorganic and organic disinfection byproducts assessed by real-time cell analysis.

Chlorine, chlorine dioxide, and ozone are widely used as disinfectants in drinking water treatments. However, the combined use of different disinfectants can result in the formation of various organic and inorganic disinfection byproducts (DBPs). The toxic interactions, including synergism, addition, and antagonism, among the complex DBPs are still unclear.

Multi-angle comparison of UV/chlorine, UV/monochloramine, and UV/chlorine dioxide processes for water treatment and reuse.

Advanced oxidation processes (AOPs) have been increasingly studied and practiced for micropollutant abatement in drinking water treatment and potable water reuse. This study conducted the multi-angle comparison of the UV/chlorine, UV/monochloramine (UV/NHCl), and UV/chlorine dioxide (UV/ClO) AOPs with respect to reactive species generation, micropollutant degradation, byproduct formation, and toxicity change. The concentrations of radicals (HO, Cl, and ClO) generated in the three AOPs followed the order of UV/chlorine > UV/NHCl > UV/ClO at an oxidant dose of 70 μM, an irradiation wavelength of 254 nm, and a pH of 7.

ClO pre-oxidation changes dissolved organic matter at the molecular level and reduces chloro-organic byproducts and toxicity of water treated by the UV/chlorine process.

The formation of undesirable chloro-organic byproducts is of great concern in the UV/chlorine process. In this study, chlorine dioxide (ClO) pre-oxidation was applied to control the formation of chloro-organic byproducts and the toxicity in UV/chlorine-treated water. The molecular-level changes in dissolved organic matter (DOM) were tracked by using Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) and ClO pre-oxidation was found to preferentially react with DOM moieties with high aromaticity level and with a carbon number of > 18, producing compounds with a higher degree of oxidation and lower aromaticity.

Hypoxia Inhibits Proliferation of Human Dermal Lymphatic Endothelial Cells via Downregulation of Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 Expression.

Objective: Lymphatic endothelial cell (LEC) proliferation is essential for lymphangiogenesis. Hypoxia induces lymphangiogenesis, but it directly inhibits LEC proliferation and the underlying mechanisms have not been fully understood. The aim of this study was to investigate the role of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in hypoxia-repressed LEC proliferation.

Sequential ClO-UV/chlorine process for micropollutant removal and disinfection byproduct control.

This study systematically revealed the feasibility of the sequential ClO-UV/chlorine process for micropollutant removal and disinfection byproduct (DBP) control. The results demonstrated that the sequential ClO-UV/chlorine process was effective for the removal of 12 micropollutants. ClO pre-treatment reduced the formation of disinfect byproducts (DBPs) in the UV/chlorine process.

Micropollutant abatement and byproduct formation during the co-exposure of chlorine dioxide (ClO) and UVC radiation.

Photolysis of ClO by UVC radiation occurs in several drinking water treatment scenarios (e.g., pre-oxidation by ClO with post-UVC disinfection or a multi-barrier disinfection system comprising ClO and UVC disinfection in sequence).

Dihydroartemisinin inhibits the expression of von Willebrand factor by downregulation of transcription factor ERG in endothelial cells.

Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, has effective antitumor and anti-inflammatory actions. von Willebrand factor (vWF), a large multifunctional glycoprotein, has a prominent function in hemostasis and is a key factor in thrombus formation. In addition, vWF has been regarded as a prospective biomarker for the diagnosis of endothelial dysfunction.

Prognostic value of plasma von Willebrand factor levels in major adverse cardiovascular events: a systematic review and meta-analysis.

Background: Prediction of major adverse cardiovascular events (MACEs) may offer great benefits for patients with coronary artery disease (CAD). Von Willebrand factor (vWF) is stored in endothelial cells and released into blood plasma upon vascular dysfunction. This meta-analysis was performed to evaluate the prognostic value of plasma vWF levels in CAD patients with MACEs.

Plasma levels of von Willebrand factor in type 2 diabetes patients with and without cardiovascular diseases: A meta-analysis.

Chronic vascular complications are the major causes of death and disability of type 2 diabetes mellitus (T2DM) patients. von Willebrand factor (vWF) is involved in pathogenesis of cardiovascular diseases (CVD). Previous studies showed elevated plasma levels of vWF in T2DM patients with CVD, but the association has not been validated.