Association Between Visceral Obesity and Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Retrospective Study.

Purpose: To investigate the association between visceral obesity and glycemic control in patients with type 2 diabetes mellitus.

Patients And Methods: A retrospective analysis involved 714 patients diagnosed with type 2 diabetes mellitus from the National Metabolic Management Center from November 2021 to February 2024. Medical data included sociodemographic data, lifestyle behaviors, and anthropometric and biochemical measurements.

Succinylated chitosan derivative restore HUVEC cells function damaged by TNF-α and high glucose in vitro and enhanced wound healing.

The inflammation of chronic wounds plays a key hindering role in the wound healing process. Slowing down the inflammatory response is significant for the repair of chronic wounds. Studies have revealed that succinate can inactivate gastrin D (GSDMD) and prevent cell pyroptosis.

Effects of traditional Chinese exercises on cardiac rehabilitation in patients with myocardial infarction: a meta-analysis of randomized controlled trials.

Objective: Traditional Chinese exercises (TCE) are excellent cardiac rehabilitation (CR) training that can effectively improve cardiorespiratory fitness. However, there is no published meta-analysis of TCE on CR in patients with myocardial infarction (MI). Therefore, this study aimed to provide a comprehensive evaluation from multiple perspectives.

Development of a Nomogram That Predicts the Risk of Coronary Heart Disease in Patients With Hyperlipidemia.

Background: Hyperlipidemia is one of the independent risk factors for the onset of coronary heart disease (CHD), and our aim is to construct a coronary risk prediction model for patients with hyperlipidemia based on carotid ultrasound in combination with other risk factors.

Methods: The nomogram risk prediction model is based on a retrospective study on 820 patients with hyperlipidemia. The predictive accuracy and discriminative ability of the nomogram were determined by receiver operating characteristic (ROC) curves and calibration curves.

Polyphenol-Rich Liupao Tea Extract Prevents High-Fat Diet-Induced MAFLD by Modulating the Gut Microbiota.

The modulation of gut microbiota dysbiosis might regulate the progression of metabolic-associated fatty liver disease (MAFLD). Here, we found that polyphenol-rich Liupao tea extract (PLE) prevents high-fat diet (HFD)-induced MAFLD in ApoE male mice accompanied by protection of the intestinal barrier and downregulation of lipopolysaccharide (LPS)-related Toll-like receptor 4 (TLR4)-myeloid differentiation primary response 88 (MyD88) signaling in the liver. Fecal microbiome transplantation (FMT) from PLE-and-HFD-treated mice delayed MAFLD development significantly compared with FMT from HFD-treated mice.

Effects of Buyang Huanwu Decoction on Intestinal Barrier, Intestinal Flora, and Trimethylamine Oxide in Rats with Heart Failure.

Objective: To explore the mechanisms of Buyang Huanwu Decoction (BYHWD) modulating the gut microbiome and trimethylamine oxide (TAMO) to exert cardioprotective effects.

Methods: Ligation of the left anterior descending coronary artery was performed in rats to induce heart failure (HF). Except for the sham-operation group (n=10), 36 operation-induced models were randomized into 3 groups using a random number table (n=12 in each group): the model group, the BYHWD group (15.

Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy.

Background: Traditional Chinese Medicine (TCM) is distinguished by Syndrome differentiation, which prescribes various formulae for different Syndromes of same disease. This study aims to investigate the underlying mechanism.

Methods: Using a strategy which integrated proteomics, metabolomics study for clinic samples and network pharmacology for six classic TCM formulae, we systemically explored the biological basis of TCM Syndrome differentiation for two typical Syndromes of CHD: Cold Congealing and Qi Stagnation (CCQS), and Qi Stagnation and Blood Stasis (QSBS).

Feasibility of reinforced post-endogenous denitrification coupling with synchronous nitritation, denitrification and phosphorus removal for high-nitrate sewage treatment using limited carbon source in municipal wastewater.

Post-endogenous denitrification (PED) process, utilizing internal rather than external carbons, has been proposed for nitrogen removal from wastewaters. However, its potential nitrogen removal capacity has not been approached, especially when facing simultaneous phosphorus removal. Here, the nitrogen removal ability of PED was further investigated by treating municipal and high-nitrate wastewaters in a novel process combined with synchronous nitritation, denitrification and phosphorus removal (SNiDPR).

Hunzeylanines A-E, Five Bisindole Alkaloids Tethered with a Methylene Group from the Roots of .

Five novel bisindole alkaloids, hunzeylanines A-E (), with an unprecedented skeleton were isolated from the roots of . Compounds represent the first examples of akuammine-pleioarpamine-type bisindole alkaloids fused with a dihydropyran unit. Their structures including absolute configurations were established through comprehensive spectroscopic data analyses and computational calculation methods.

Structurally Diverse Indole Alkaloids with Vasorelaxant Activity from .

Six new structurally diverse indole alkaloids, melohemsines J-M (-), 11-hydroxy-Δ-vincamine (), and 11-hydroxy-16--Δ-vincamine (), and 15 known alkaloids were isolated from the leaves and twigs of Diels. These new compounds and their absolute configurations were determined through spectroscopic data analyses, X-ray diffraction, and computational methods. Melohemsine J () is the first example of a melodinus-type alkaloid possessing a 6/6/5/5/6/5 hexacyclic skeleton and containing a tetrahydrofuro[2,3-]pyridine-2(3)-one unit.

[Stable Nitrite Accumulation and Phosphorus Removal from High-nitrate and Municipal Wastewaters in a Combined Process of Partial Denitrification and Denitrifying Phosphorus Removal (PD-DPR)].

In this study, a novel process combining partial denitrification (PD, NO-N→NO-N) and denitrifying phosphorus removal (DPR) in an anaerobic-anoxic-aerobic sequencing batch reactor (SBR) was developed. By comprehensively controlling the influent C/N ratio, anaerobic drainage ratio, and anoxic duration, the nitrite accumulation and phosphorus removal performance of a system treating high-strength nitrate and municipal wastewaters was investigated. The results showed that, after 140 days, the nitrate-to-nitrite transformation ratio (NTR) was 80.

Hunterines A-C, Three Unusual Monoterpenoid Indole Alkaloids from .

Three new monoterpenoid indole alkaloids (MIAs), hunterines A-C (-), were isolated from Compound possesses a unique skeleton with an unprecedented azabicyclo[4.3.1]decane ring system.

Two New Flavonoids from the Nuts of .

Two new flavonoids, calquiquelignan M (), calquiquelignan N (), along with nine known compounds (-), were isolated from the nuts of (Palmae). The new structures, including absolute configurations, were established by a combination of spectroscopic data and electronic circular dichroism (ECD) calculation. The known compounds were identified by comparing their spectroscopic data with reported in the literature.

Achieving deep-level nutrient removal via combined denitrifying phosphorus removal and simultaneous partial nitrification-endogenous denitrification process in a single-sludge sequencing batch reactor.

The feasibility of coupling denitrifying phosphorus removal (DPR) with simultaneous partial nitrification-endogenous denitrification (SPNED) was investigated in a single-sludge sequencing batch reactor for deep-level nutrient removal from municipal and nitrate wastewaters. After 160-day operation, the DPR process simultaneously reduced most PO-P and NO-N anoxically, and the SPNED process achieved further total nitrogen (TN) removal at low dissolved oxygen condition with TN removal efficiency of 90.8%.

[Nitrogen and Phosphorus Removal from Low C/N Municipal Wastewater Treated by a SPNDPR System with Different Aeration and Aerobic Times].

An anaerobic (180 min)/aerobic operated sequencing batch reactor (SBR) fed with urban sewage was optimized by regulating the aeration quantity to investigate the deep-level nitrogen (N) and phosphorus (P) removal. The amount of aeration was regulated by adjusting the volume of gas per unit volume of reactor passed in unit time, when the unit is L·(min·L), from 0.125 L·(min·L) gradually to 0.

Evaluating the potential for sustaining mainstream anammox by endogenous partial denitrification and phosphorus removal for energy-efficient wastewater treatment.

This study demonstrated a novel process configuration for sustaining mainstream anammox by integrating the anammox and endogenous partial denitrification-and-phosphorus removal (EPDPR) in two-stage sequencing batch reactors (SBRs). In the EPDPR-SBR, high nitrate-to-nitrite transformation (68.2%) and P removal (99.

[Operating Characteristics of a DPR-SNED System Treating Low C/N Municipal Wastewater and Nitrate-containing Sewage].

In order to realize the simultaneous treatment of low C/N municipal wastewater and high nitrate wastewater, a sequencing batch reactor (SBR), inoculated with activated sludge, was used to initiate the denitrifying phosphorus removal coupled with simultaneous nitrification and endogenous denitrification (DPR-SNED). The anaerobic/anoxic/hypoxic durations and dissolved oxygen (DO) concentration were appropriately controlled, and the nitrogen and phosphorus removal characteristics were examined. The experimental results demonstrated that, in the anaerobic/hypoxia operation mode, with an anaerobic duration of 3 h and DO concentration of 0.

[Denitrification and Phosphorus Removal from Low C/N Urban Sewage Based on a Post-Partial Denitrification AOA-SBR Process].

This study focuses on the investigation of the nitrogen (N) and phosphorus (P) removal characteristics of a combination of enhanced phosphorus removal (EBPR) with simultaneous partial nitrification endogenous denitrification (SPND) and post-partial denitrification process. An anaerobic/aerobic/anoxic (A/O/A) operated sequencing batch reactor (SBR) fed with urban sewage was optimized by regulating the aeration rate and anoxic time. Based on this optimization, deep-level nitrogen and phosphorus removals from low C/N urban sewage could be realized.

[Effect of Different Sludge Retention Time (SRT) Operations on the Nutrient Removal Characteristics of a SNEDPR System].

This study focuses on the nitrogen (N) and phosphorus (P) removal characteristics in a simultaneous nitrification endogenous denitrification and phosphorus removal (SNEDPR) system operating at different sludge retention time (SRT). Four extended anaerobic/low aerobic (dissolved oxygen:0.5-1.

[Effect of the Influent C/P Ratio on the Nutrient Removal Characteristics of the SNEDPR System].

This study focuses on the nitrogen (N) and phosphorus (P) removal characteristics in a simultaneous nitrification-endogenous denitrification and phosphorus removal (SNEDPR) system at different influent C/P ratios. An extended anaerobic/low aerobic (dissolved oxygen:0.5-1.

[Simultaneous Nitrogen and Phosphorus Removal Characteristics of An Anaerobic/Aerobic Operated SPNDPR System Treating Low C/N Urban Sewage].

This study focused on the nitrogen (N) and phosphorus (P) removal performance optimization of simultaneous partial nitrification-endogenous denitrification and phosphorus removal (SPNDPR) systems. An anaerobic (180 min)/aerobic operated sequencing batch reactor (SBR) fed with domestic wastewater was used for investigating the startup and optimization of SPNDPR by regulating the aeration rate and aerobic duration time. The experimental results showed that at an aerobic aeration rate of 0.

Remarkable functions of -3 hydroxy and phosphocholine groups in 1,2-diacyl--glycerolipids to induce clockwise (+)-helicity around the 1,2-diacyl moiety: Evidence from conformation analysis by H NMR spectroscopy.

Cell-membrane glycerolipids exhibit a common structural backbone of asymmetric 1,2-diacyl--glycerol bearing polar head groups in the -3 position. In this study, the possible effects of -3 head groups on the helical conformational property around the 1,2-diacyl moiety in the solution state were examined. H NMR Karplus relation studies were carried out using a series of 1,2-dipalmitoyl--glycerols bearing different -3 substituents (namely palmitoyl, benzyl, hydrogen, and phosphates).

An easy α-glycosylation methodology for the synthesis and stereochemistry of mycoplasma α-glycolipid antigens.

Mycoplasma fermentans possesses unique α-glycolipid antigens (GGPL-I and GGPL-III) at the cytoplasm membrane, which carry a phosphocholine group at the sugar primary (6-OH) position. This paper describes a practical synthetic pathway to a GGPL-I homologue (C(16:0)) and its diastereomer, in which our one-pot α-glycosylation method was effectively applied. The synthetic GGPL-I isomers were characterized with (1)H NMR spectroscopy to determine the equilibrium among the three conformers (gg, gt, tg) at the acyclic glycerol moiety.