Biological properties and potential application of extracts and compounds from different medicinal parts (bark, leaf, staminate flower, and seed) of : A review.

() is a relict plant belonging to the Eucommiaceae family. Each part of including the bark, leaf, staminate flower, and seed, contains various active ingredients, that are edible and have medicinal value. This review summarizes the literatures on the functional properties of flavonoids, phenols, terpenoids, and polysaccharides in different parts of .

Transcriptomic analysis the mechanisms of anti-osteoporosis of desert-living Cistanche herb in ovariectomized rats of postmenopausal osteoporosis.

Desert-living Cistanche herb (DC), as a traditional Chinese medicine for tonifying kidney yang, is often used to treat postmenopausal osteoporosis (PMOP). Total phenylethanoid glycosides are instruction ingredients for discrimination and assay according to the China pharmacopoeia for DC. This research aimed to reveal the anti-osteoporosis mechanism of total phenylethanoid glycosides of DC (PGC) by transcriptomic analysis of ovariectomized rats.

Identifying and analyzing the key genes shared by papillary thyroid carcinoma and Hashimoto's thyroiditis using bioinformatics methods.

Background: Hashimoto's thyroiditis (HT) is a chronic autoimmune disease that poses a risk factor for papillary thyroid carcinoma (PTC). The present study aimed to identify the key genes shared by HT and PTC for advancing the current understanding of their shared pathogenesis and molecular mechanisms.

Methods: HT- and PTC-related datasets (GSE138198 and GSE33630, respectively) were retrieved from the Gene Expression Omnibus (GEO) database.

Postmenopausal osteoporosis: a bioinformatics-integrated experimental study the pathogenesis.

Postmenopausal osteoporosis (PMOP) is a chronic bone metabolic disease, which often causes fractures and various complications, it causes a great social and economic burden, and it is urgent to use modern research techniques to elucidate the pathogenesis of PMOP. At the same time, because of the complex physiological and pathological interaction mechanism between osteoporosis and sarcopenia, the correlation research has become a hot topic. Ovary removal is a commonly used experimental method to study the endocrine system of female animals, and it is also the best animal model to study PMOP.

Attenuation of Infection in by YtnP, a -acyl Homoserine Lactonase from T-1.

In this experiment, the quorum quenching gene of T-1 was cloned and expressed, and the effect against infection of ATCC 7966 was evaluated in vitro and vivo. The BLAST results revealed a 99% sequence identity between the gene of T-1 and its homolog in sub sp. BSP1, and the dendroGram showed that the similarity in the YtnP protein in T-1 was 100% in comparison with 3610, which was categorized as the Aidc cluster of the MBL family.

Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet.

Ethnopharmacological Relevance: Eucommia ulmoides Oliv. leaves are the dry leaves of Eucommia ulmoides Oliv. Modern studies have shown that Eucommia ulmoides Oliv.

[Research progress on traditional Chinese medicine in preventing and treating cerebral ischemia injury based on "nose-brain" pathway].

Due to the increasing incidence of central nervous system diseases,especially the increasing incidence and mortality of stroke,brain-targeted drug delivery has attached more and more attention. Nasal administration,as one of the ways of brain-targeted administration,can effectively make the drug delivered to the brain in a targeted way after by passing the blood-brain barrier,providing a new idea for the treatment of central nervous system diseases. Therefore,it is a promising administration way.

Effects of dodder total flavone on polycystic ovary syndrome rat models induced by DHEA combined HCG.

Aims: Explore the effects of dodder total flavone on polycystic ovary syndrome (PCOS) rat models induced by dehydroepiandrosterone (DHEA) combined human chorionic gonadotropin (HCG).

Methods: Except the blank group, the rest of the rats were injected with DHEA 6 mg/100 g on the back of the neck and 1.5 IU HCG each day, for 21 consecutive days.

Effects of compound lobelia oral liquid on acute pharyngitis rabbits model.

Aims: Explore the effect of compound lobelia oral liquid on acute pharyngitis rabbits model caused by ammonium hydroxide, evaluate its curative effect.

Methods: Acute pharyngitis rabbit model was prepared by ammonia spray at pharyngeal. After 1 h of the last administration, score the pharyngeal tissue symptoms of rabbits under the condition of naked eyes (score according to the score criteria).

Effect of Shuangjinlian mixture on oral ulcer model in rat.

Objective: To observe the effect of common clinical drug Shuangjin Lian mixture on rats with oral ulcer and discuss its mechanism.

Methods: Sodium carboxymethyl cellulose caused leukocyte aggregation in rats, observed the anti-inflammatory effect of Shuangjin mixture. 3 mm * 3 mm size ulcer surface in the oral cavity of rats was caused by 90% phenol solution, to observe the therapeutic effect and anti-inflammatory effect of Shuangjinlian mixture on rats with oral ulcers.

Effects of Baihe Dihuang powder on chronic stress depression rat models.

Purpose: Explore the effect of Baihe Dihuang powder on chronic stress depression rat models.

Methods: Chronic stress depression rat models were established with different stimuli for 21 days. At the same time, the drug was administered for 21 consecutive days.

Anti-inflammatory effect and the effect on acute pharyngitis rats model of compound Lobelia oral liquid.

Objective: Observe anti-inflammatory effect and the effect on acute pharyngitis rats model induced by ammonia water of compound Lobelia oral liquid, providing experimental basis for its clinical use.

Methods: Use egg white establish foot swelling rats model and use carboxymethyl cellulose establish white blood cell migration rats model. Then observe the anti-inflammatory effect of compound Lobelia oral liquid.

Effect of total phenolic acids on focal cerebral ischemia reperfusion injury rats model.

Objective: Explore the possible protective effect of total phenolic acids on cerebral ischemia reperfusion injury rats.

Methods: Focal cerebral ischemia reperfusion rats model were established by linear thrombus. Nimodipine group, Naoluotong group, the high, middle and low dose of total phenolic acids groups were given related drugs via intragastric administration before operation for seven days, once a day.

The Quorum Quenching Bacterium Bacillus licheniformis T-1 Protects Zebrafish against Aeromonas hydrophila Infection.

Quorum sensing, bacterial cell-to-cell communication via small signaling molecules regulates virulence in many bacterial pathogens, and is a promising target for antivirulence therapy, which may inhibit virulence rather than cell growth and division. Herein, Bacillus strains capable of degrading QS molecules from freshwater environments were screened as potential aquaculture probiotics. A total of 34 Bacillus strains were isolated.

Effect of 3:7 ratio of Astragalus total saponins and Curcumin on the diabetic nephropathy rats model.

Objective: Study the effect of the 3:7 ratio of Astragalus total saponins and Curcumin on the model of diabetic nephropathy rats, and explore its mechanisms.

Methods: Diabetic nephropathy rats model was established by high-fat and high-sugar feed feeding combined with streptozotocin (STZ) injection in sublingual vein. Measured fasting blood glucose of rats on the 10, 20 and 30th day, and measured urine protein content in urine of rats on 30th days.

Effect of syrup on bronchial asthma mice model.

Purpose: To investigate the effect of syrup on bronchial asthma mice model.

Methods: Sixty Kunming mice were randomly divided into normal control group, bronchial asthma model group, low-, middle-, and high-dose syrup groups. Bronchial asthma was induced by injection of ovalbumin combined smoking.

Effects of different components of Mao Dongqing's total flavonoids and total saponins on transient ischemic attack (TIA) model of rats.

Unlabelled: To study the effects of the different components of the total flavonoids and total saponins from Mao Dongqing's active site on the rats of TIA model, determine the optimal reactive components ratio of Mao Dongqing on the rats of TIA. TIA rat model was induced by tail vein injection of tert butyl alcohol, the blank group was injected with the same amount of physiological saline, then behavioral score wasevaluated. Determination the level of glutamic acid in serum, the activity of Na+-K+-ATP enzyme, CA-ATP enzyme and Mg-ATP enzyme in Brain tissue, observe the changes of hippocampus in brain tissue, the comprehensive weight method was used to evaluate the efficacy of each component finally.