Publications by authors named "Mengels A"
Study Question: Are cumulative pregnancy rates better if supernumerary embryos are vitrified on Day 5/6 instead of Day 3?
Summary Answer: The results do not show a significant difference in cumulative pregnancy rates between the Day 3 and Day 5/6 vitrification groups.
What Is Known Already: Pregnancy and live birth rates following IVF or ICSI treatment are higher after extended embryo culture and blastocyst transfer (Day 5/6) compared to cleavage-stage (Day 3) transfer. Cumulative pregnancy rates from one oocyte retrieval (OR) cycle show no significant difference after fresh and frozen embryo transfers, but only one study has used vitrification for the cryopreservation of supernumerary embryos while four studies have used a slow freezing protocol.
Article Synopsis
- - This study investigated whether the reasons for oocyte reception (OR) or embryo reception (ER) affect reproductive and obstetric outcomes at a tertiary fertility center, reviewing 584 cycles from 194 patients and analyzing 27 relevant studies from various databases.
- - The major reasons for OR/ER were categorized into three groups: failure of autologous assisted reproductive technology, premature ovarian insufficiency (POI), and genetic disease carrier status.
- - Results showed no significant differences in pregnancy rates, miscarriage rates, and obstetric outcomes among the groups, consistent with existing literature, although some studies noted poorer outcomes for patients with POI from chemotherapy or radiation treatment.