Developing a rapid predictive model for falls in older hospitalized patients.

Background: This study was aimed to identify the independent risk factors for falls n hospitalized older patients and develop a corresponding predictive model.

Methods: A retrospective observational study design was adopted, comprising 440 older patients with falls history and 510 older patients without falls history during hospitalization. Data collected included demographic information, vital signs, comorbidities, psychiatric disorder, function absent, current medication, other clinical indicators.

sp. nov., a novel denitrifying bacteria isolated from the Yellow Sea and transfer of and to the genus as comb. nov. and nom. nov.

A Gram-stain-negative and rod-shaped bacterium, designated strain CY04, was isolated from a sediment sample collected from the Yellow Sea. CY04 exhibited the highest 16S rRNA gene sequence similarity of 98.7 % to CY05, followed by the similarities of 98.

Genome-based taxonomic classification of the genus Sulfitobacter along with the proposal of a new genus Parasulfitobacter gen. nov. and exploring the gene clusters associated with sulfur oxidation.

Background: The genus Sulfitobacter, a member of the family Roseobacteraceae, is widely distributed in the ocean and is believed to play crucial roles in the global sulfur cycle. However, gene clusters associated with sulfur oxidation in genomes of the type strains of this genus have been poorly studied. Furthermore, taxonomic errors have been identified in this genus, potentially leading to significant confusion in ecological and evolutionary interpretations in subsequent studies of the genus Sulfitobacter.

Insights into the regulatory role of bacterial sncRNA and its extracellular delivery via OMVs.

Small noncoding RNAs (sncRNAs) play important regulatory roles in bacterial physiological processes and host-pathogen interactions. Meanwhile, bacterial outer membrane vesicles (OMVs), as naturally secreted outer membrane structures, play a vital role in the interaction between bacteria and their living environment, including the host environment. However, most current studies focus on the biological functions of sncRNAs in bacteria or hosts, while neglecting the roles and regulatory mechanisms of the OMVs that encapsulate these sncRNAs.