A prospective cohort study of cochlear implantation as a treatment for tinnitus in post-lingually deafened individuals.

Background: Cochlear implants have helped over one million individuals restore functional hearing globally, but their clinical utility in suppressing tinnitus has not been firmly established.

Methods: In a decade-long study, we examined longitudinal effects of cochlear implants on tinnitus in 323 post-lingually deafened individuals including 211 with pre-existing tinnitus and 112 without tinnitus. The primary endpoints were tinnitus loudness and tinnitus handicap inventory.

List Equivalency and Critical Differences of a Mandarin Bamford-Kowal-Bench Sentence in Babble Noise Test for Adults and Preschool Children With Normal Hearing.

Purpose: The purpose of this study was to determine the speech recognition equivalence of Mandarin Bamford-Kowal-Bench (BKB) sentence lists with adults and children with normal hearing.

Method: A total of 32 lists, each of nine sentences, were compiled from a corpus of BKB-like sentences with paired babble in Mandarin. Interlist equivalence, critical differences, and sensitivity of performance to signal-to-noise ratio (SNR) were examined.

NRT test in auditory neuropathy patients with cochlear implants.

Conclusion: In patients with auditory neuropathy (AN), waveforms of neural response telemetry (NRT) could be present, showing characteristics of low incidence, low differentiation, and large variation.

Objective: To study the characteristics of NRT in AN patients who had received cochlear implants (CIs).

Methods: NRT data for seven AN patients who had received Nucleus CIs were retrospectively analyzed.

Preliminary performance of cochlear implants in post-lingual patients with auditory neuropathy.

Conclusions: Auditory restoration can be obtained by using cochlear implants (CIs) in post-lingual patients with auditory neuropathy (AN). However, improvements in postoperative speech recognition for these patients varied.

Objectives: The primary purpose of this study was to assess the postoperative performances of two post-lingual AN patients after receiving CIs.

Development of a corpus of Mandarin sentences in babble with homogeneity optimized via psychometric evaluation.

Objective: To develop a corpus of sentences in babble noise that is suitable for Mandarin-speaking children. Two experiments were conducted with specific aims of (1) developing sentence material that is grammatically and semantically within the linguistic abilities of children; and (2) improving the efficiency of the test by equalizing the relative intelligibility of individual items in sentences.

Design And Study Sample: Sentences were extracted from spoken material of Chinese children aged between 4 and 5 years of age.

[Preliminary clinical research of cochlear implantation in elderly and pre-elderly patients with profound hearing loss].

Objective: To explore the safety and efficacy of cochlear implantation among elderly patients with severe to profound hearing loss.

Methods: Eight pre-elderly and elderly patients with an medium age of 58 years who suffered from bilateral severe to profound sensorineural hearing loss received cochlear implantation between November 2008 and November 2009. The patients' tolerance to implant surgery and the occurrence of complications were observed.

[Mutation of Gap junction protein beta 2 gene and treatment outcome of cochlear implantation in cochlear implantation recipients].

Objective: To investigate the Gap junction protein beta 2 (GJB2) gene mutation in cochlear implantation (CI) recipients and the treatment outcome of CI in the CI recipients with GJB2 gene mutation.

Methods: Peripheral blood samples were collected from 253 CI recipients with autosomal recessive non-syndromic hearing impairment (NSHI), 174 males and 79 females, aged (8 +/- 9) (112 months-52.7 years), and 301 children with normal hearing level as controls.

[Mapping of gene underlying autosomal dominant non-syndromic hearing loss(DFNA)].

Hereditary non-syndromic sensorineural hearing loss is a genetically highly heterogeneous group of disorders. To date, at least 50 loci for autosomal dominant non-syndromic sensorineural hearing loss (DFNA) have been identified by linkage analysis. Here we report a huge family with late onset autosomal dominant hereditary non-syndromic hearing loss.

[Rating evaluation of the effect of pre-lingual cochlear implanted's aural/oral rehabilitation by questionnaires].

Objective: To evaluate the effect of cochlear implanted's aural/oral rehabilitation using rating evaluation method by questionnaires, to analyze the relationship between rehabilitation effect and its possible influence factors including type of implant, age at surgery, pathology, etc, and to explore the rating questionnaire method for cochlear implanted's aural/oral rehabilitation effect evaluation.

Methods: Ninety-seven pre-lingual cochlear implanted's were involved in this investigation, all of which were severe or profound deafness before implantation. Interviewed the implanted's parents or teachers, asking them to rate the implanted's aural ability objectively from 1 to 8 according to Categories of Auditory Performance (CAP) and speech producing ability from 1 to 5 according to Speech Intelligibility Rating (SIR), then analyzed the relationship between effect of aural/oral rehabilitation represented by CAP/SIR rating results and its possible 9 influence factors including type of implant, age at surgery, pathology, duration of hearing loss, hearing aid wearing, inserting length of electrodes, implanted period, rehabilitation mode and financial conditions.

[Refractory recovery function of electrical auditory on the survival auditory nerve in cochlear implant recipients].

Objective: To evaluate the cochlear implant recipient's electrical auditory temporal properties in order to estimate the maximum stimulating rate which can be reached when they adopted some speech coding strategies based on time mechanism, such as continuous interleaved sampling (CIS).

Methods: Thirty-eight Nucleus CI24 cochlear implant recipients were divided into 4 groups by etiology and history. Their survival auditory nerve fibers' refractory recovery time function was measured via neural response telemetry (NRT).

[Electrically evoked compound action potential thresholds of pediatric cochlear implant recipients and its clinical application].

Objective: To investigate the possibility of using pediatric cochlear implant mapping protocol, to estimate the psychophysical levels based on the electrically evoked compound action potential (ECAP) threshold measured with the neural response telemetry (NRT) capabilities of cochlear corporation's CI24M device.

Methods: ECAP amplitude growth functions were regressed via NRT 3.0 software to determine ECAP threshold.