Publications by authors named "Meng-Yuan Ge"
Article Synopsis
- The study presents an efficient dual-catalyzed reaction that combines photoredox and nickel catalysis for cyanoalkylation of enamides.
- A variety of enamides and cycloketone oxime esters were used, resulting in β-cyanoalkylated enamide structures that are both versatile and geometrically defined.
- The practical application of this method was demonstrated through large-scale reactions and the ability to modify biologically active molecules.
Herein, a new strategy for the synthesis of monofluoroalkenes via employing α-fluoroacrylic acids and -hydroxyphthalimide (NHPI) redox-active esters as coupling partners has been developed. This decarboxylative reaction enabled the formation of C(sp)-C(sp) bonds to provide a practical and efficient approach for the construction of a variety of monofluoroalkenes, which are key structural motifs in organic chemistry, under mild reaction conditions. The protocol exhibited excellent functional group compatibility and delivered monofluoroalkene products with excellent -stereoselectivity.
View Article and Find Full Text PDF