Publications by authors named "Meng-You Zeng"
Curr Med Sci
February 2020
Article Synopsis
- Sinomenine (SN) has been clinically used for treating autoimmune diseases like lupus and rheumatoid arthritis, showing benefits such as anti-inflammation and suppression of immune responses.
- In a study, it was found that SN effectively inhibits macrophage activation induced by lipopolysaccharide (LPS) by down-regulating inflammatory cytokines and key proteins in the TLR4/NF-κB signaling pathway.
- The research suggests that SN's mechanism involves blocking the TLR4/NF-κB pathway, which could lead to new therapeutic strategies for managing inflammatory responses.
