Publications by authors named "Meng-Yin Gu"
Purpose: Non-invasive methods for predicting pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) can provide distinct leverage in the management of patients with locally advanced rectal cancer (LARC). This study aimed to investigate whether including the golden-angle radial sparse parallel (GRASP) dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) perfusion parameter (K), in addition to tumor regression grading (TRG) and apparent diffusion coefficient (ADC) values, can improve the predictive ability for pCR.
Methods: Patients with LARC who underwent nCRT and subsequent surgery were included.
Article Synopsis
- The study investigates the clinical significance of the apparent diffusion coefficient (ADC) from the RESOLVE technique in assessing features of distal rectal cancer and its relationship with Ki-67 expression.
- Analysis of data from 112 patients revealed that higher ADC values correlated with lower clinical stages and well-differentiated tumors, while lower ADC values associated with higher Ki-67 expression, indicating more aggressive cancer.
- The findings suggest that ADC values are a promising noninvasive imaging biomarker for predicting the biological characteristics of distal rectal cancer.
Article Synopsis
- COVID-19, specifically the SARS-CoV-2 Omicron subvariant BA.2, is primarily affecting many countries, and understanding its impact on patients is crucial for better clinical management.
- A study analyzed 805 patients with mild or moderate BA.2 infections, revealing that the majority experienced mild symptoms like fever and cough, while 6.6% showed signs of pneumonia on HRCT scans.
- The findings indicated that lung issues were generally mild, predominantly presenting as ground-glass opacity, and most patients eventually recovered after short-term follow-up.