Visualization of the relationship between metabolism and lung diseases from the perspective of bibliometric analysis: research trends and future prospects.

Background: Extensive research has examined the role of metabolism in lung disease development, yet a comprehensive literature review remains absent despite numerous publications.

Objective: This study aims to visualize and assess the advancements in research on metabolism and its role in lung diseases.

Methods: Publications from January 1, 1991, to April 30, 2024, related to lung diseases and metabolism were sourced from the Web of Science Core Collection and analyzed using CiteSpace 6.

Over-activation of iNKT cells aggravate lung injury in bronchopulmonary dysplasia mice.

Bronchopulmonary dysplasia (BPD) is a severe lung disease in preterm infants, the abnormal proliferate and differentiate ability of type II epithelial cells (AEC II) is the key to the pathological basis of BPD. Mechanisms regarding abnormal AEC II in BPD remain unclear. The present work investigated the role and mechanisms of invariant natural killer T (iNKT) cells in lung disorder in BPD using public datasets, clinical samples, a hyperoxia-induced BPD mouse model and AEC II-iNKT cells transwell co-culture system.