Publications by authors named "Meng-Xia Ning"
BMC Biotechnol
December 2019
Article Synopsis
- Interferon-gamma (IFN-γ) is a crucial component of the immune response with roles in antiviral actions and inflammation, and this study aimed to create a monoclonal antibody (mAb) against caprine IFN-γ using mice.
- The researchers produced recombinant caprine IFN-γ in E. coli and successfully developed a hybridoma (designated as 2C) that secretes mAb, which specifically recognizes the IFN-γ protein, as confirmed through various assays.
- The developed mAb 2C is effective in detecting IFN-γ in goats, showing promise for understanding its expression during contagious ecthyma infections.
Front Immunol
August 2020
Article Synopsis
- The gut microbiota, consisting of over a trillion microbes, forms a mutually beneficial relationship with mammals, contributing to immune system development and pathogen defense.
- The microbiota utilizes several mechanisms to enhance the innate immune response, including the secretion of antimicrobial peptides and activation of the inflammasome.
- Key immune molecules like IL-22, IL-17, and IL-10 are produced in response to these interactions, showcasing the gut microbiota's role in protecting the host from infections.
