Publications by authors named "Meng-Wei Tsai"
Int Immunopharmacol
January 2024
Article Synopsis
- Encapsulating peritoneal sclerosis (EPS) is a serious complication for patients undergoing peritoneal dialysis, leading to high risks during surgery for intestinal obstruction.
- The study shows that melatonin treatment can significantly lower harmful immune cell types (Th1 and Th17) and inflammatory cytokines while increasing beneficial IL-10 levels in mice with EPS.
- Melatonin’s effectiveness may be due to its ability to inhibit the activation of dendritic cells and interfere with the signaling pathways involved in immune response, suggesting it has potential as a preventive treatment for EPS in dialysis patients.
