Publications by authors named "Meng-Tao Xu"
Article Synopsis
- The study focuses on the mitochondrial calcium uniporter (MCU) and its role in controlling mitochondrial calcium levels, which are crucial for energy metabolism and mitophagy in pancreatic ductal epithelial cells during acute pancreatitis.
- Researchers induced acute pancreatitis-like changes in human pancreatic cells using caerulein, observing an increase in MCU expression and mitochondrial calcium levels, which led to alterations in mitophagy markers.
- Inhibiting the MCU reversed the changes caused by caerulein, suggesting that the MCU enhances mitophagy through the regulation of the PINK1/Parkin pathway in these cells during acute pancreatitis.
Background: Magnetic resonance (MR) imaging provides a unique, noninvasive diagnostic platform to quantify the physiological and biochemical variables of skeletal muscle at rest. This study was to investigate the difference in thigh skeletal muscles between snowboarding halfpipe athletes and healthy volunteers via multiparametric MR imaging.
Methods: A comparative study was conducted between 12 healthy volunteers and 14 snowboarding halfpipe athletes.