Phase-change composite filled natural nanotubes in hydrogel promote wound healing under photothermally triggered drug release.

It is of great importance to treat a bacterial-infected wound by a smart dressing capable of delivering antibiotics in a smart manner without causing drug resistance. The construction of smart release nanocontainers responsive to near-infrared (NIR) laser irradiation in an on-demand and stepwise way is a promising strategy for avoiding the emergence of multidrug-resistant bacteria. Here, we develop a hydrogel composite made of alginate and nanotubes with an efficient NIR-triggered release of rifampicin and outstanding antibacterial ability.

Solid Lipid Nanoparticles Formulated for Transdermal Aconitine Administration and Evaluated In Vitro and In Vivo.

In this study, solid lipid nanoparticles were formulated for transdermal delivery of aconitine to improve its safety and permeability. Aconitine-loaded solid lipid nanoparticles were formulated as an oil-in-water microemulsion. Drug encapsulation efficiencies for these formulations were higher than 85%, and correlated positively with levels of surfactant and oil matrix.

A linear comprehensive adsorption model of hydrogen on super activated carbon under supercritical conditions.

The adsorption isotherms of hydrogen on super activated carbon were measured systematically, covering a temperature range of 93-293 K at 20 K intervals and pressures up to 7 MPa. All the experimental data were linearized by adopting the coordinates ln ln(n) vs 1/(ln P). The results indicate that the adsorption limit (P(lim), n(lim)) exists virtually at high pressure and has a certain physical meaning.