Ulcerative colitis (UC) is a rising global health issue, characterized by dysfunction in the intestinal barrier and immune response, which poses serious health risks.
Research indicates that factors like intestinal mucosal damage, stem cell dysfunction, and gut microbiota imbalance contribute to UC's development.
The Notch signaling pathway plays a crucial role in regulating intestinal health by influencing various cells and functions, offering potential therapeutic insights into UC treatment, especially through traditional Chinese medicine approaches.