RLFDDA: a meta-path based graph representation learning model for drug-disease association prediction.

Background: Drug repositioning is a very important task that provides critical information for exploring the potential efficacy of drugs. Yet developing computational models that can effectively predict drug-disease associations (DDAs) is still a challenging task. Previous studies suggest that the accuracy of DDA prediction can be improved by integrating different types of biological features.

The influence of "small private online course + flipped classroom" teaching on physical education students' learning motivation from the perspective of self-determination theory.

Objective: The study aimed to enhance the learning motivation of college physical education students and improve their learning outcomes. Based on the perspective of the self-determination theory, this study explores the influence of "Small Private Online Course (SPOC) + flipped classroom" teaching on the learning motivation of students majoring in physical education and profoundly analyzes the influencing factors and promotion paths of learning motivation using this model.

Materials And Methods: A total of four classes (64 students) of physical education majors in a university were selected and randomly divided into an experimental group (34 students) and a control group (30 students).

[Comparison of wear resistance and flexural strength of three kinds of bulk-fill composite resins].

Purpose: To compare the abrasion resistance and flexure strength of three bulk-fill resin composites with an universal nano-hybrid composite resins.

Methods: The specimens were prepared with three kinds of bulk fill composites (SDR , sonicfill, Tetric N-Ceram Bulk Fill) and an universal nano-hybrid composite resins(Herculite Precis). 10 mm in diameter × 2mm in height specimens were prepared for abrasion resistance, while 2 mm in width × 2 mm in depth×25 mm in length specimens were prepared for flexure strength.

[The effect of various irrigants on apically extruded debris: an in vitro study].

Purpose: To compare the amount of debris extruded apically from root canals when different irrigants were used.

Methods: Fifty-eight extracted single-rooted human mandibular premolars with straight root canals were used. The teeth were randomly divided into control group (group A, n=7) and 3 experimental groups (group B,C,D,n=17).