Publications by authors named "Meng-Liang Ge"
[Study on the association of clinical characteristic, CD4+ and level of HIV viral load among 690 initial HIV-infection].
Zhonghua Liu Xing Bing Xue Za Zhi
October 2007
Article Synopsis
- The study aimed to analyze the relationship between CD4+ cell count, HIV viral load, and clinical characteristics of HIV-1 positive patients at the time of their AIDS diagnosis.
- A total of 690 HIV-infected individuals from Beijing, predominantly male, showed various modes of transmission, with significant incidences from homosexual and heterosexual contacts, along with cases from blood-related transmission.
- The findings revealed late disease identification often resulting in severe immunodeficiency and complications, highlighting the necessity for improved awareness and access to medical care for individuals living with HIV.
AIM:We have previously reported that inducible over-expression of Bak may prolong cell cycle in G(1) phase and lead to apoptosis in HCC-9204 cells. This study is to investigate whether p27(KIP1) plays an important role in this process.METHODS:In order to elucidate the exact function of p27(KIP1) in this process, a zinc inducible p27(KIP1) stable transfectant and transient p27(KIP1)-GFP fusion transfectant were constructed.
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