Publications by authors named "Meng-Han Nie"
J Nanobiotechnology
October 2024
Article Synopsis
- Bone macrophages interact with bone marrow mesenchymal stem cells (BMSCs) and their regulation through exosomes is vital for understanding bone-related diseases, especially glucocorticoid-associated osteonecrosis of the femoral head (GA-ONFH).
- Research found an increase in M1 macrophages in GA-ONFH, but the relationship between these macrophages and BMSCs in the context of glucocorticoids is not well understood.
- Results showed that glucocorticoid-stimulated M1 macrophages inhibit the osteogenic differentiation of BMSCs and promote their adipogenic differentiation through exosomes and the microRNA miR-1a-3p.
