Publications by authors named "Meng-Dan Zhou"
Article Synopsis
- Diabetes can lead to heart issues through a process called cardiac fibrosis, where tissue becomes stiff and scarred; EZH2 is a key player in this process but its specific role in the heart isn't fully understood.
- The study used rat and mouse models to look at how diabetes affects heart function and fibrosis, measuring changes in heart cells and proteins when exposed to high glucose levels.
- Findings suggest that high glucose conditions increase specific modifications on histones (H3K27 trimethylation) while decreasing EZH2 activation, implicating a signal pathway (AMPK/EZH2/PPAR-γ) that drives the harmful changes in heart cells associated with diabetic fibrosis.
Objectives: The objectives of this study were to present an accessible C-shaped partial stapled hemorrhoidopexy (C-PSH) in the treatment of grade IV hemorrhoids and to assess long-term outcomes of this technique compared with circular stapled hemorrhoidopexy (CSH).
Methods: Conventional CSH kits combined with an intestinal spatula were used for performing C-PSH. A total of 256 patients with grade IV hemorrhoids referred to Hangzhou Third People's Hospital between January 2016 and June 2017 were obtained: 122 (47.
Objective: To explore the objectivity and time-effect of stimulating effect at acupoint with PGLA in the healthy person, and to provide a basis for the rational interval of minimally invasive embedding of PGLA.
Methods: Before embedding, 8 h, 3rd, 7th, 10th, 14th day after embedding, medical imaging magnetic resonance imaging (MRI) scanning technique was used to collect local T2WI pressure-lowering and T2-Mapping 8 echoes sequence image of left Zusanli (ST 36) in 8 cases of healthy person. The T2-Mapping 8 echoes sequence image was generated by the relevant software to the T2-Mapping image and the local T2 value was measured.