Publications by authors named "Meng-Dan Zhang"

Article Synopsis
  • Fungal diseases pose a significant threat to agricultural production, prompting the need for new antifungal agents.
  • Researchers isolated 14 new brominated aromatic butenolides and six known analogues from a soft coral-derived endophytic fungus, demonstrating their antifungal potency against various plant pathogens.
  • The most promising compound showed significant effects by disrupting nutrient signaling in target fungi, suggesting its potential as a novel agricultural antifungal drug, especially effective against diseases affecting papayas.
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Background: Tooth development, as one of the major mineralized tissues in the body, require fine-tuning of mineralization micro-environment. The interaction between dental epithelium and mesenchyme plays a decisive role in this process. With epithelium-mesenchyme dissociation study, we found interesting expression pattern of insulin-like growth factor binding protein 3 (IGFBP3) in response to disruption of dental epithelium-mesenchyme interaction.

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