Publications by authors named "Meng-Chun Wu"

Study Objectives: To efficiently improve the scoring competency of scorers with varying levels of experience across regions in Taiwan, we developed a training program with a cloud-based polysomnography scoring platform to evaluate and improve interscorer agreement.

Methods: A total of 70 scorers from 34 sleep centers in Taiwan (job tenure: 0.5-39.

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The aim of this study was to understand the distribution of the personal care products nonylphenol (NP), triclosan (TCS), benzophenone-3 (BP-3), and caffeine in the sludges from three wastewater treatment plants (WWTP-A, -B, and -C) in southern Taiwan. The four compounds were analyzed from activated sludge and dewatered sludge samples, and then the samples were treated with pressure-assisted ozonation under different conditions and removal efficiencies. All four target compounds were detected, especially NP, which was detected in the highest concentrations in the activated sludges of WWTP-A and dewatered sludges of WWTP-C at 17.

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Article Synopsis
  • * The research involved a bi-directional Mendelian randomization analysis of 15,996 healthy Taiwanese individuals, examining the causal relationship between platelet count and hypertension.
  • * The study concluded that higher platelet counts significantly increase the risk of hypertension, while the reverse effect of hypertension on platelet count was found to be insignificant.
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Invasive blood pressure (IBP) measurement is common in the intensive care unit, although its association with in-hospital mortality in critically ill patients with hypertension is poorly understood. A total of 11,732 critically ill patients with hypertension from the eICU-Collaborative Research Database (eICU-CRD) were enrolled. Patients were divided into 2 groups according to whether they received IBP.

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This study reports on a sediment toxicity test developed with a native amphipod strain of Ptilohyale barbicornis where sediments from 10 estuarine stations along the western coastline of Taiwan were evaluated with respect to trace metals and PAHs. The test was validated by determining dose-response relationships for aqueous copper, and cadmium and sodium dodecyl sulfate as well as copper-spiked sediment, showing a sensitivity of P. barbicornis indicating its capability serving as a toxicity test species.

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Article Synopsis
  • The study focuses on a hybrid two-component system (TCS) that regulates swarming ability and biofilm formation in an opportunistic pathogen causing various infections.
  • Researchers determined the crystal structures of two key proteins, HptB and the receiver domain of HK PA1611, to investigate their interactions for transferring a phospho-ryl group.
  • The findings reveal unique structural features and interactions between these proteins that differ from other TCS complexes, enhancing our understanding of the TCS and potentially guiding new treatments for infections.
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This study utilized the freshwater amphipod (Hyalella azteca) for the indication of contamination risk levels of sediment-associated contaminants in the Erren (ER1∼ER10) and Sanye Rivers (SY1∼SY5) which were contaminated by metal scrap and smelting industries for decades. Toxicity identification evaluations involving the manipulation of pore water and whole-sediment samples were conducted to identify causative pollutants. Impacts on the aquatic environment were then evaluated in order to explore how industrial development led to contaminant accumulation in sediments and resulted in biological effects.

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We assessed 22 selected endocrine-disrupting compounds (EDCs) and other emerging, potentially endocrine-active compounds with estrogenic activity from the waters of the Wuluo River, southern Taiwan. This watershed receives high amounts of livestock and untreated household wastewaters. The river is surrounded by concentrated animal feedlot operations (CAFOs).

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Objective: To determine whether the use of a nasogastric tube influences swallowing function in stroke patients with dysphagia.

Design: Before-after trial.

Setting: Primary care center.

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This study used comparison with videofluoroscopic examination of swallowing (VFES) to examine the validity of a 100-ml water swallowing test (WST) in assessing swallowing dysfunction. Fifty-nine consecutive outpatients (15 females, 44 males) with clinically suspected dysphagia were enrolled in this study. Each subject underwent a 100-ml WST followed by VFES.

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