Exterior exposure estimation using a one-compartment toxicokinetic model with blood sample measurements.

Exposure assessment of individuals exposed to certain chemicals plays an important role in the analysis of occupational-as well as environmental-health problems. Biological monitoring, as an alternative to direct environmental measurements, may be applied to relate the exterior exposure with the amount of individual intake. In this paper, we estimate individuals' (inhalation) exposure retrospectively from their blood concentrations via a simplified one-compartment toxicokinetic model.