Publications by authors named "Meng Yi Ren"
Background: Idiopathic normal pressure hydrocephalus (iNPH) is highly prevalent among elderly individuals, and there is a strong correlation between telomere length and biological aging. However, there is limited evidence to elucidate the relationship between telomere length and iNPH. This study aimed to investigate the associations between telomere length and iNPH using the Mendelian randomization (MR) method.
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- - Epigenetic modifications play a key role in plant development, particularly in the formation of pollen walls and male fertility, as seen in the EFD gene in Arabidopsis, which is crucial for these processes.
- - The study identifies that DRM2 can compensate for the defects caused by EFD mutations, indicating its role as a potential DNA methyltransferase that influences plant gene regulation.
- - EFD works through a regulatory relationship with the HB21 gene, where it represses HB21's transcription, affecting other genes necessary for pollen formation and further insights into the epigenetic regulation of anther development are provided.
Slow development has been shown to be a general mechanism to restore the fertility of thermo-sensitive and photoperiod-sensitive genic male sterile (TGMS and PGMS) lines in Arabidopsis. rpg1 is a TGMS line defective in primexine, which is essential for pollen wall pattern formation. Here, we showed that RPG1-GFP was highly expressed in microsporocytes, microspores, and pollen grains but not in the tapetum in the complemented transgenic line, suggesting that microsporocytes are the main sporophytic cells for primexine formation.
View Article and Find Full Text PDFPhotoperiod- and thermosensitive genic male sterility (P/TGMS) lines are widely used in crop breeding. The fertility conversion of Arabidopsis () TGMS lines including , which is defective in callose wall formation, relies on slow development under low temperatures. In this study, we discovered that also exhibits PGMS.
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