Objectives: To investigate how maternal gene polymorphisms and their interactions with periconceptional folic acid supplementation are associated with the incidence of ventricular septal defects (VSD) in offspring.
Methods: A case-control study was conducted, recruiting 426 mothers of infants with VSD under one year old and 740 mothers of age-matched healthy infants. A questionnaire survey collected data on maternal exposures, and blood samples were analyzed for genetic polymorphisms.
Background: The prognosis for patients with advanced metastatic cervix cancer (MCC) is poor, and this disease continues to pose a considerable therapeutic challenge. Despite the administration of first-line regimens consisting of cisplatin, paclitaxel, and bevacizumab, survival rates for patients with metastasis remain poor. The emergence of bispecific antibodies (BsAbs) offers a novel treatment option for patients diagnosed with MCC.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
July 2022
Objectives: To study the association of maternal methylenetetrahydrofolate dehydrogenase 1 () and methylenetetrahydrofolate dehydrogenase 2 () gene polymorphisms with congenital heart disease (CHD) in offspring.
Methods: A hospital-based case-control study was conducted. The mothers of 683 children with CHD alone who attended Hunan Children's Hospital, from November 2017 to March 2020 were enrolled as the case group, and the mothers of 740 healthy children who attended the same hospital during the same period and did not have any deformity were enrolled as the control group.
Objective: This study aimed to assess the associations between maternal drug use, cytochrome P450 ( ) genetic polymorphisms, and their interactions with the risk of congenital heart defects (CHDs) in offspring.
Methods: A case-control study involving 569 mothers of CHD cases and 652 controls was conducted from November 2017 to January 2020.
Results: After adjusting for potential confounding factors, the results show that mothers who used ovulatory drugs (adjusted odds ratio [a ] = 2.
Gas hydrate technology holds great potential in energy and environmental fields, and achieving efficient gas hydrate formation is critical for its industrial application. Graphene is a novel carbon-based nanostructured material with excellent thermal conductivity and a large specific surface area. Therefore, the use of graphene-based materials for the promotion of gas hydrate formation might be feasible and has aroused a lot of interests.
View Article and Find Full Text PDFFront Bioeng Biotechnol
April 2020
Methane is a greenhouse gas and significantly contributes to global warming. Methane biofiltration with immobilized methane-oxidizing bacteria (MOB) is an efficient and eco-friendly approach for methane elimination. To achieve high methane elimination capacity (EC), it is necessary to use an exceptional support material to immobilize MOB.
View Article and Find Full Text PDFMethane is a greenhouse gas with significant global warming potential. The methane-oxidizing bacteria (MOB) immobilized on biocarrier could perform effectively and environmentally in methane elimination. To further improve the efficiencies of MOB immobilization and methane elimination, the surface biocompatibility of biocarrier needs to be improved.
View Article and Find Full Text PDFMethane in exhaust gas from biogas upgrading process, which is a greenhouse gas, could cause global warming. The biofilter with immobilized methane-oxidizing bacteria (MOB) is a promising approach for methane removal, and the selections of inoculated MOB culture and support material are vital for the biofilter. In this work, five MOB consortia were enriched at different methane concentrations.
View Article and Find Full Text PDFMacroalgae biomass has been considered as a promising feedstock for biogas production. In order to improve the efficiency of anaerobic digestion (AD) of macroalgae, semi-continuous fermentation was conducted to examine the effects of organic loading rate (OLR) on biogas production from Macrocystis pyrifer. Results showed that, under OLRs of 1.
View Article and Find Full Text PDFBiogas upgrading is essential for the comprehensive utilization of biogas as substitute of natural gas. However, the methane in the biogas can be fully recovered during the upgrading process of biogas, and the exhaust gas produced during biogas upgrading may contain a very low concentration of methane. If the exhaust gas with low concentration methane releases to atmosphere, it will be harmful to environment.
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