Summary of emergency treatment experience of acute severe urethral trauma in pre-pubertal girls.

Purpose: To summarize our treatment experience of acute urethral trauma in pre-pubertal girls.

Methods: We retrospectively analyzed six pre-pubertal girls with acute severe urethral trauma who were admitted to our hospital from April 2003 to April 2023 and followed up.

Results: All six patients had pelvic fractures and vaginal injuries, and one had a rectal injury.

Experimental and Model Calculation Research on Shrinkage of Hybrid Fiber-Reinforced Recycled Aggregate Concrete.

Recycled aggregate concrete (RAC), which is made by replacing all natural coarse and fine aggregates with recycled aggregate, plays a significant role in improving the recycling rate of construction materials, reducing carbon emissions from construction, and alleviating ecological degradation issues. However, due to its low strength and significant shrinkage and deformation problems, RAC has limited application. The effort of fiber type, fiber admixture, and fiber hybridization on autogenous shrinkage were studied to improve the structural safety of building materials and broaden the application of RAC.

Predictive Value of Monocyte to High-Density Lipoprotein Cholesterol Ratio for Target Lesion Revascularization in Patients With Drug-Eluting Stent Implantation.

Background: Severe in-stent restenosis (ISR) following the implantation of drug-eluting stent (DES) can lead to recurrent angina pectoris or even acute myocardial infarction, thereby necessitating target lesion revascularization (TLR). Prior studies have confirmed the correlation between the monocyte to high-density lipoprotein cholesterol ratio (MHR) and ISR after DES implantation. The potential of MHR to predict TLR following DES implantation remains an area of ongoing research and may have significant clinical implications.

The host susceptibility/resistance-related genes and gut microbial characteristics in -infected chickens.

Pullorum disease is a bacterial disease caused by in chickens, which is characterized by gastrointestinal infection and diarrhea. In traditional perspectives, research on pullorum disease primarily focused on clinical symptoms, epidemiological characteristics, and the pathogenic sites. This study, however, approaches the subject from the standpoint of host genetic basis and gut microbiota.

Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics.

With the growth of clinical cancer single-cell RNA sequencing studies, robust differential expression methods for case/control analyses (e.g., treatment responders vs.

Microfibrillated cellulose reinforced polyethyleneimine cryogels fabricated via cryo-induced chemical crosslinking for enhanced removal of albumin-bound bilirubin.

Bilirubin exists as albumin-bound complexes in the bloodstream of patients with hyperbilirubinemia. Developing adsorbents with high removal efficiency for albumin-bound bilirubin and excellent hemocompatibility is essential for effective hemoperfusion therapy. Herein, microfibrillated cellulose-reinforced polyethyleneimine cryogels (PEI/MFC) with robust mechanical properties were fabricated through cryo-induced chemical crosslinking, using bis(vinylsulphonyl)methane (BVSM) as chemical cross-linker.

Toward Reversible Crystalline-to-Amorphous Guest-Induced Transitions in Manganese(III) Carboxylate Metal-Organic Frameworks.

Metal-organic frameworks (MOFs) are an interesting class of inorganic/organic hybrid materials with a wide scope of applications. Although manganese is an abundant metal, the synthesis of Mn(III)-containing MOFs has not been widely studied due to the relative redox sensitivity of this species. We therefore investigated the self-oxidation of manganese(II) nitrate in the presence of aromatic dicarboxylic linkers in alcohols, discovering a series of new Mn(III)-MOFs.

The effect of physical activity on sleep disorders in pregnant people: a meta-analysis of randomized controlled trials.

Background: Sleep disorders are highly prevalent in pregnant people and have been associated with significant complications and morbidities for both pregnant people and their offspring. Despite this, the management of sleep issues during pregnancy remains suboptimal. There is an urgent need to explore novel treatment approaches that are safe, feasible, and widely implementable in daily routines.

Final Overall Survival and Molecular Data Associated with Clinical Outcomes in Patients Receiving Ipatasertib and Abiraterone in the Phase 3 IPATential150 Trial.

Background And Objective: In the phase 3 IPATential150 trial, ipatasertib addition to abiraterone significantly reduced the risk of disease progression in men with metastatic castration-resistant prostate cancer (mCRPC) with PTEN loss on immunohistochemistry (IHC), but not in the intention-to-treat (ITT) population. Here we report the final overall survival (OS) analysis and present results for prespecified and exploratory biomarker analyses.

Methods: Patients were randomized to receive ipatasertib (400 mg once daily) or placebo.

Cu Site-Enhanced Adsorption and Crown Ether-Reconfigured Interfacial DO Promote Electrocatalytic Dehalogenative Deuteration.

Electrocatalytic dehalogenative deuteration is a sustainable method for precise deuteration, whereas its Faradaic efficiency (FE) is limited by a high overpotential and severe D evolution reaction (DER). Here, Cu site-adjusted adsorption and crown ether-reconfigured interfacial DO are reported to cooperatively increase the FE of dehalogenative deuteration up to 84% at -100 mA cm. Cu sites strengthen the adsorption of aryl iodides, promoting interfacial mass transfer and thus accelerating the kinetics toward dehalogenative deuteration.

A machine learning technique for optimizing load demand prediction within air conditioning systems utilizing GRU/IASO model.

Air conditioning systems are widely used to provide thermal comfort in hot and humid regions, but they also consume a large amount of energy. Therefore, accurate and reliable load demand forecasting is essential for energy management and optimization in air conditioning systems. Within the current paper, a novel model on the basis of machine learning has been presented for dynamic optimal load demand forecasting in air conditioning systems.

Survival after venoarterial extracorporeal membrane oxygenation for acute high-risk Pulmonary Embolism: A meta-analysis of comparative studies.

Objective: The survival benefit of venoarterial Extracorporeal Membrane Oxygenation (ECMO) for the management of acute high-risk pulmonary embolism (PE) remains unclear. This meta-analysis combines data from comparative studies to assess the risk of mortality after ECMO vs standard care in the management of acute high-risk PE.

Methods: Databases of PubMed, CENTRAL, Scopus, Web of Science, and Embase were searched from 01 January 2000 to 24 March 2023 for comparative studies with at least 10 patients/group comparing ECMO vs standard treatment.

Clinical characteristics, complications and satisfaction of megameatus intact prepuce (MIP) hypospadias variant: a 15 year retrospective study.

Background: To analyze the clinical characteristics, complications and patients satisfaction of MIP hypospadias variant.

Methods: A retrospective analysis was performed for 31 patients with MIP admitted to our hospital from January 2008 to February 2023. All enrolled patients underwent telephone follow-up and a survey was conducted on the satisfaction of patients and their families.

Selective production of olefins from methanol over a heteroatomic SAPO-34 zeolite.

The methanol-to-olefins (MTO) process has the potential to bridge future gaps in the supply of sustainable lower olefins. Promoting the selectivity of propylene and ethylene and revealing the catalytic role of active sites are challenging goals in MTO reactions. Here, we report a novel heteroatomic silicoaluminophosphate (SAPO) zeolite, SAPO-34-Ta, which incorporates active tantalum(V) sites within the framework to afford an optimal distribution of acidity.

Defect-Induced Electron Localization Promotes DO Dissociation and Nitrile Adsorption for Deuterated Amines.

Electrochemical reductive deuteration of nitriles is a promising strategy for synthesizing deuterated amines with DO as the deuterated source. However, this reaction suffers from high overpotentials owing to the sluggish DO dissociation kinetics and high thermodynamic stability of the C≡N triple bond. Here, low-coordinated copper (LC-Cu) is designed to decrease the overpotential for the electrosynthesis of the precursor of Melatonin-d, 5-methoxytryptamine-d, by 100 mV with a 68 % yield (Faradaic efficiency), which is 4 times greater than that of high-coordinated copper (HC-Cu).

Acute Niclofolan Intoxication Led to Stillbirth: A Case Report.

Niclofolan is a commonly used veterinary drug worldwide. We reported a case of acute niclofolan intoxication in a pregnant woman. We recorded in detail her toxic symptoms, including nausea, vomiting, asthenia, blurred vision, and aberrant blood values.

Interface-engineered non-volatile visible-blind photodetector for in-sensor computing.

Ultraviolet (UV) detection is extensively used in a variety of applications. However, the storage and processing of information after detection require multiple components, resulting in increased energy consumption and data transmission latency. In this paper, a reconfigurable UV photodetector based on CeO/SrTiO heterostructures is demonstrated with in-sensor computing capabilities achieved through interface engineering.

Effects of neuropeptide F signaling on feeding, growth and development of Plutella xylostella (L.) larvae.

The neuropeptide F (NPF) signaling, comprising NPF and neuropeptide F receptor (NPFR), role in regulating insect behaviors and physiological processes. We cloned the genes encoding NPF and NPFR from Plutella xylostella, a notorious pest of cruciferous crops. Notably, the NPF gene produced two splicing variants, Px-NPF1 and Px-NPF2, with distinct expression patterns.

miR-141-3p inhibited BPA-induced proliferation and migration of lung cancer cells through PTGER4.

Unlabelled: The chemical substance bisphenol A (BPA) is widely used in household products, and its effect on human health has frequently been the focus of research. The aim of this study was to explore the potential molecular regulatory mechanism of BPA on the proliferation and migration of lung cancer cells. In this study, the H1299 and A549 lung cancer cell lines were selected as the study objects.

Near telomere-to-telomere assembly of the Tarim pigeon (Columba livia) genome.

Pigeons serve as important model animals and commercial poultry. The Tarim pigeon, as a breed of Columba livia, is a locally indigenous breed unique to China. While the genome of C.

Direct Preparation of Ultrathin Polymer Membranes on Porous Substrates for the Separation of Helium From Methane.

Ultrathin polymer membranes on porous substrates exhibit excellent gas and ion permeability and have important applications in many fields, such as membrane separation and batteries. However, there is still a lack of facile and general methods for the direct preparation of ultrathin polymer membranes on porous substrates, especially from polymer solutions. Within this work, a new strategy to fabricate centimeter-size ultrathin polymer membranes (thickness down to 16 nm) is presented directly on porous supports by using the liquid-liquid interfacial spin-coating technique.

Near telomere-to-telomere genome assembly of Mongolian cattle: implications for population genetic variation and beef quality.

Background: Mongolian cattle, a unique breed indigenous to China, represent valuable genetic resources and serve as important sources of meat and milk. However, there is a lack of high-quality genomes in cattle, which limits biological research and breeding improvement.

Findings: In this study, we conducted whole-genome sequencing on a Mongolian bull.

A pilot study of the relationship between salivary microbial characteristics and endocrine and immune function in patients with burning mouth syndrome.

Objectives: To explore the potential role of oral bacteria in the pathogenesis of burning mouth syndrome (BMS).

Materials And Methods: Fifteen patients with BMS and 15 healthy controls were enrolled in this study. The relative abundance and diversity of salivary bacterial strains were analyzed using metagenomic DNA sequencing.