Structural basis for the effects of thermal treatment on soybean seed β-conglycinin.

The production of soy protein in the food industry is inextricably linked to the thermal sterilization process. To gain a deeper understanding of the changes in protein structure during this process, we compared the structural effects of typical thermal sterilization methods (pasteurization and ultra-high temperature sterilization) on β-conglycinin. Chemical characterization of the solutions showed that two thermal sterilization methods did not affect the primary structure and overall morphology of β-conglycinin.

Unsupervised Domain Adaptation for Cross-Modality Cerebrovascular Segmentation.

Cerebrovascular segmentation from time-of-flight magnetic resonance angiography (TOF-MRA) and computed tomography angiography (CTA) is essential in providing supportive information for diagnosing and treatment planning of multiple intracranial vascular diseases. Different imaging modalities utilize distinct principles to visualize the cerebral vasculature, which leads to the limitations of expensive annotations and performance degradation while training and deploying deep learning models. In this paper, we propose an unsupervised domain adaptation framework CereTS to perform translation and segmentation of cross-modality unpaired cerebral angiography.

Electrospinning Meets Heterostructures in Lithium-Sulfur Batteries.

Lithium-sulfur (Li-S) batteries are recognized as a most promising energy storage technology for their high theoretical energy density, abundant sulfur resources, and environmental friendliness. Nonetheless, practical applications of Li-S batteries are currently hindered by obstacles such as the shuttle effect of lithium polysulfides (LiPSs), sluggish reaction kinetics, and the formation of Li dendrites. Heterostructured electrocatalysts can achieve synergistic adsorption-catalysis for LiPSs by regulating the component composition to accelerate sulfur electrochemical reaction and guide the uniform deposition of Li.

The mechanisms of social network on subjective well-being from a life course perspective: the mediating role of individual resilience.

Background: Social networks are an important factor affecting Chinese residents' subjective well-being (SWB). Dividing social networks from the functional perspective can elucidate the SWB effect more effectively. This paper aims to explore how different social network supports affect SWB, further analyze the mechanism of individual resilience between them, and observe its changing trend throughout life.

The value of slough in wounds for the diagnosis of microbiology cultivation.

Slough is not currently a recommended microbiology culture specimen. The aim of our work is to analyse the concordance of results between slough and swab samples for cultures. A single-centre, retrospective, cross-sectional study involving patients (n = 131) with hard to heal wounds was conducted from October 2022 to October 2023.

Dynamic urban morphology mapping in Chinese cities based on local climate zone approach.

Urbanization have been significantly reshaping the form of urban areas and natural landscapes, leading to complex urban morphologies. In 2012, the Local Climate Zone (LCZ) classification was proposed to address this issue and has since been widely adopted in urban climate studies globally. Despite its prevalence, literature on dynamic mapping of urban morphology remains sparse, making it difficult to delve into the study of urban renewal year by year.

Association between ethylene oxide exposure and cognitive function in older adults from NHANES data.

Ethylene Oxide (EO), a volatile organic compound, has garnered considerable attention for its potential impact on human health. Yet, the ramifications of EO exposure on the cognitive functionality of the elderly remain unclear. The aim of this study is to determine whether EO exposure in the elderly correlates with cognitive function.

SCN10A gene polymorphism is associated with pain sensitivity and postoperative analgesic effects in patients undergoing gynecological laparoscopy.

Background: Postoperative pain intensity is influenced by various factors, including genetic variations. The SCN10A gene encodes the Nav1.8 sodium channel protein, which is crucial for pain signal transmission in peripheral sensory neurons.

Nuclear Overexpression of SAMHD1 Induces M Phase Stalling in Hepatoma Cells and Suppresses HCC Progression by Interacting with the Cohesin Complex.

Emerging evidence suggests that the sterile alpha-motif (SAM) and histidine-aspartate (HD) domain-containing protein 1 (SAMHD1) is implicated in various cancers, including hepatocellular carcinoma (HCC). However, its precise role in tumor cells and the underlying mechanisms remain unclear. This study aimed to investigate the expression patterns, prognostic values, and functional role of SAMHD1 in HCC progression.

HubNet: An E2E Model for Wheel Hub Text Detection and Recognition Using Global and Local Features.

Automatic detection and recognition of wheel hub text, which can boost the efficiency and accuracy of product information recording, are undermined by the obscurity and orientation variability of text on wheel hubs. To address these issues, this paper constructs a wheel hub text dataset and proposes a wheel hub text detection and recognition model called HubNet. The dataset captured images on real industrial production line scenes, including 446 images, 934 word instances, and 2947 character instances.

Decoding the origins, spread, and global risks of mcr-9 gene.

Background: The global spread of the plasmid-mediated mcr (mobilized colistin resistance) gene family presents a significant threat to the efficacy of colistin, a last-line defense against numerous Gram-negative pathogens. The mcr-9 is the second most prevalent variant after mcr-1.

Methods: A dataset of 698 mcr-9-positive isolates from 44 countries is compiled.

Correlation between anesthetic concentration and low Apgar scores in neonates born via Cesarean sections under general anesthesia.

Objectives: This study aimed to compare plasma concentrations of anesthetic drugs administered during Cesarean section with low Apgar score in neonates deliveried under general anesthesia and analyze associated risk factors.

Methods: Data from 76 neonates undergoing Cesarean section under general anesthesia with blood concentrations of anesthetic drugs were analyzed. A low Apgar score was defined as ≤ 7.

PathoTracker: an online analytical metagenomic platform for Klebsiella pneumoniae feature identification and outbreak alerting.

Clinical metagenomics (CMg) Nanopore sequencing can facilitate infectious disease diagnosis. In China, sub-lineages ST11-KL64 and ST11-KL47 Carbapenem-resistant Klebsiella pneumoniae (CRKP) are widely prevalent. We propose PathoTracker, a specially compiled database and arranged method for strain feature identification in CMg samples and CRKP traceability.

CHRM3 (rs2165870) gene polymorphism is related to postoperative vomiting in female patients undergoing laparoscopic surgery. Prospective observational study.

Background: Postoperative nausea and vomiting are common complications after surgery, and female patients are more likely to experience these adverse events. The goal of this study was to explore the relationship between the CHRM3 rs2165870 polymorphism and postoperative vomiting incidence in female patients who underwent laparoscopic surgery.

Methods: Two hundred female patients who underwent elective laparoscopic surgery with subsequent patient-controlled intravenous analgesia using dexmedetomidine and sufentanil were prospectively enrolled.

Study on rock fracture mechanism and hydraulic fracturing propagation law of heterogeneous tight sandstone reservoir.

Hydraulic fracturing technology is an effective way to develop tight sandstone reservoirs with low porosity and permeability. The tight sandstone reservoir is heterogeneous and the heterogeneity characteristics has an important influence on fracture propagation. To investigate hydraulic fracture performance in heterogeneous tight reservoir, the X-ray diffraction experiments are carried out, the Weibull distribution method and finite element method are applied to establish the uniaxial compression model and the hydraulic fracture propagation model of heterogeneous tight sandstone.

A Prognostic Model Incorporating Relevant Peripheral Blood Inflammation Indicator to Predict Postherpetic Neuralgia in Patients with Acute Herpes Zoster.

Objective: To determine the risk of postherpetic neuralgia (PHN) in patients with acute herpes zoster (HZ), this study developed and validated a novel clinical prediction model by incorporating a relevant peripheral blood inflammation indicator.

Methods: Between January 2019 and June 2023, 209 patients with acute HZ were categorized into the PHN group (n = 62) and the non-PHN group (n = 147). Univariate and multivariate logistic regression analyses were conducted to identify risk factors serving as independent predictors of PHN development.

Tracking intra-species and inter-genus transmission of KPC through global plasmids mining.

Klebsiella pneumoniae carbapenemase (KPC) poses a major public health risk. Understanding its transmission dynamics requires examining the epidemiological features of related plasmids. Our study compiled 15,660 bla-positive isolates globally over the past two decades.

Study on the Mass Spectrometry Cleavage Pattern of Quinolone Antibiotics.

Rationale: Quinolone antibiotics are extensively used clinically for human treatment and in agriculture. However, improper and excessive use can lead to the persistence of quinolone residues in animal tissues, potentially accumulating in the human body and posing health risks. Investigating the correlation between mass spectrometry cleavage patterns and molecular structural features enhances the analytical framework for detecting trace or unknown impurities in quinolones.

Photo-Assisted Rechargeable Metal Batteries: Principles, Progress, and Perspectives.

The utilization of diverse energy storage devices is imperative in the contemporary society. Taking advantage of solar power, a significant environmentally friendly and sustainable energy resource, holds great appeal for future storage of energy because it can solve the dilemma of fossil energy depletion and the resulting environmental problems once and for all. Recently, photo-assisted energy storage devices, especially photo-assisted rechargeable metal batteries, are rapidly developed owing to the ability to efficiently convert and store solar energy and the simple configuration, as well as the fact that conventional Li/Zn-ion batteries are widely commercialized.

Association of methyl donor nutrients dietary intake and sleep disorders in the elderly revealed by the intestinal microbiome.

Currently, sleep disorders (SD) in the elderly are gaining prominence globally and are becoming a significant public health concern. Methyl donor nutrients (MDNs), such as vitamin B, vitamin B, folate, and choline, have been reported to have the potential to improve sleep disorders. Moreover, MDNs help to maintain gut flora homeostasis, and are closely associated with the development of SD.