Effectiveness of "Sukhi Hrudaya - heart health guide for women" on heart health awareness in a tertiary care setting of Manipal.

Background: Cardiovascular diseases (CVDs) are a major global burden, particularly in low- and middle-income countries, leading to higher rates of chronic CVDs and increased risks of morbidity and mortality. Offering women a comprehensive Information, Education, and Communication health guide can significantly help combat CVDs by enhancing their awareness regarding heart health. Our aim was to determine the effectiveness of "Sukhi Hrudaya - heart health guide for women" on awareness regarding heart health.

Terminological subset of ICNP® for people with chronic kidney disease on hemodialysis.

Objectives: To construct and validate a terminological subset of the International Classification of Nursing Practice (ICNP®) for people with chronic kidney disease on hemodialysis.

Method: Methodological study developed in accordance with the recommendations of the International Council of Nurses (ICN) and the Brazilian method, in the following stages: construction of ND/NO and NI statements of the ICNP® for nursing practice for people with chronic kidney disease on hemodialysis, based on previously constructed specialized terminology and in accordance with Wanda Horta's Basic Human Needs Theory; and content validation of the statements by focus groups with specialist nurses. The Content Validity Index was used and statements ≥ 0.

A biomarkers study of human skin fibroblasts exposition to glyphosate-based herbicide using an untargeted and targeted metabolomics approach.

Metabolomics is a valuable tool to assess glyphosate exposure and its potential impact on human health. However, few studies have used metabolomics to evaluate human exposure to glyphosate or glyphosate-based herbicides (GBHs). In this study, an untargeted and targeted metabolomics approach was applied to human skin fibroblasts exposed to the GBH Roundup (GLYP-R).

An exploratory study of volatile and semi-volatile organic compounds in PM atmospheric particles from an outdoor environment in Brazil.

The development of methods for determining volatile and semi-volatile organic compounds in public spaces has become necessary to identify potential health and environmental risks. This study presents a practical methodology for sampling, extracting, detecting, and identifying these compounds in a vehicular traffic region in Belo Horizonte, Brazil. The methodology uses direct-immersion solid phase microextraction (DI-SPME) and static headspace (SHS) to extract SVOCs/VOCs.

Volatilome Study of Jabuticaba (Plinia cauliflora) Using a Hydrophilic Microporous Cartridge with Direct Immersion Solid Phase Microextraction and Gas Chromatography System With a Hybrid Quadrupole Time-Of-Flight Mass Spectrometry.

Jabuticaba (Plinia cauliflora) is a typical subtropical Brazilian fruit with unique organoleptic properties and a high nutritional value. This study shows a qualitative analysis of jabuticaba peels with volatile and semi-volatile components harvested from Minas Gerais, Brazil. A new device, the hydrophilic microporous cartridge, was developed to extract jabuticaba peels' volatile/semi-volatile components using a solid-phase microextraction method by direct immersion.

Use of Telenursing in the conservative treatment of patients with chronic renal insufficiency: scoping review.

Objective: to map the evidence of the use of telenursing in adherence to treatment and promotion of self-care in patients with chronic renal insufficiency undergoing conservative treatment.

Method: scoping review study, with selection of documents indexed in eight databases and two catalogs of theses and dissertations. Additionally, the reference lists of selected studies were consulted.

Development of new PDMS in tube extraction microdevice for enhanced monitoring of polycyclic aromatic hydrocarbons and their derivatives in water.

Contamination by polycyclic aromatic hydrocarbons (PAHs) is an urgent environmental concern, given its atmospheric dispersion and deposition in water bodies and soils. These compounds and their nitrated and oxygenated derivatives, which can exhibit high toxicities, are prioritized in environmental analysis contexts. Amid the demand for precise analytical techniques, comprehensive two-dimensional chromatography coupled with mass spectrometry (GCxGC/Q-TOFMS) has emerged as a promising tool, especially in the face of challenges like co-elution.

Evaluation of a long-lasting microbial larvicide against Culex quinquefasciatus and Aedes aegypti under laboratory and a semi-field trial.

Background: Microbial larvicides containing both LysiniBacillus sphaericus and Bacillus thuringiensis svar. israelensis (Bti) insecticidal crystals can display advantages for mosquito control. This includes a broader action against larvae that are refractory to the Binary (Bin) toxin from L.

Dietary Profile of Patients with Inflammatory Bowel Disease in Clinical Remission-A Preliminary Study.

Imbalanced dietary intake is associated with the development of inflammatory bowel diseases (IBDs) and is often observed during the active phases of Crohn's disease (CD) and ulcerative colitis (UC). Cumulative data also suggest the potential for dietary manipulation in avoiding IBD relapse. However, there is a paucity of dietary data from patients in clinical remission to guide such an approach.

Analysis of 4725 Cases of Gluteal Augmentation with Intramuscular Fillers: A Clinical Cohort Study.

Background: In recent years, the aesthetic market has become more prominent for being not only a tool to correct unwanted features but also a social means for improving quality of life. The use of 30% polymethylmethacrylate (PMMA) as a gluteal filler has grown in popularity all over the world, being sought after by men and women for body remodeling because it provides a natural look as well as significant long-lasting results.

Methods: A retrospective, multicenter study analyzed the medical records of 2801 patients who underwent a total of 4725 gluteal filler procedures between January 2009 and December 2021 at the different locations of Clínica Leger.

Ab initio investigation of the geometrical behavior in solution and electronic structure of the anion complexes [bis(1,3-dithiole-2-thione-4,5-dithiolate)M], for M = Bi(III), Sb(III), and Zn(II).

Context: 1,3-Dithiole-2-thione-4,5-dithiolate (dmit) ligands are known for their conductive and optical properties. Dmit compounds have been assessed for use in sensor devices, information storage, spintronics, and optical material applications. Associations with various metallic centers endow dmit complexes with magnetic, optical, conductive, and antioxidant properties.

Middle-Range Theory of Occupational Stress in Health Professionals.

Introduction: Occupational stress affects health professionals; however, no literature was found on the middle-range theory for this outcome in health professionals.

Methods: Methodological study for the theoretical validation of a nursing diagnosis using the theoretical framework of Walker and Avant and the Betty Neuman systems models. The research was conducted in five stages: comprehension of the system model; selection and review of studies; development of the conceptual-theoretical-empirical structure; elaboration of a diagram and proposition of a nursing diagnosis; and evaluation of the empirical adequacy of the theory and validity of the system model.

Clinical validation of the terminological subset for people with chronic kidney disease undergoing conservative treatment.

Objective: To clinically validate a terminological subset of the International Classification for Nursing Practice (ICNP®) to care for people with chronic kidney disease undergoing conservative treatment.

Method: Prospective study of clinical validation assessment of 117 nursing diagnoses/outcomes statements and 199 nursing intervention statements. It was operationalized through the following steps: implementation of the Nursing Process in an outpatient clinic in Southeast Brazil; preparation of case studies; analysis of agreement between specialist nurses.

Resistant to the Binary Toxin from Displays a Consistent Downregulation of Pantetheinase Transcripts.

resistance to the binary (Bin) toxin, the major larvicidal component from , is associated with mutations in the gene, encoding the Bin-toxin receptor. Downregulation of the transcript was found in the transcriptome of larvae resistant to the IAB59 strain, which produces both the Bin toxin and a second binary toxin, Cry48Aa/Cry49Aa. Here, we investigated the transcription profiles of two other mosquito colonies having Bin resistance only.

The use of carbon dioxide and intense pulsed light laser for the treatment of hypertrophic burn scars: A case series.

Introduction: Hypertrophic scarring is a common and debilitating consequence of burn scars. While there is limited evidence for current treatment options, laser therapy has been shown to be effective, low risk and minimally invasive. This study assesses the use of carbon dioxide lasers and intense pulsed light devices in the treatment of hypertrophic burn scars.

ICNP® terminological subset for people with diabetic foot ulcer in primary health care.

Objectives: to elaborate an ICNP® terminological subset for people with diabetic foot ulcers in Primary Health Care.

Methods: this is a methodological study that followed five steps: 1) Identification of relevant terms for the patients through an integrative literature review and official documents in the area; 2) Mapping of terms identified with ICNP® terms; 3) Construction of statements of nursing diagnoses, outcomes and interventions; 4) Structuring of a terminological subset with the Self-Care Deficit Theory; and 5) Content validity of statements constructed with nurses from a programmatic area in Rio de Janeiro.

Results: the subset developed is composed of 81 diagnoses/outcomes and 583 nursing interventions, organized into universal, change and development requirements.

Construction and validation of nursing diagnoses for premature newborns.

Objective: To build and validate nursing diagnoses based on the International Classification of Nursing Practice (ICNP®) for premature newborns admitted to the Neonatal Intensive Care Unit.

Method: Methodological study based on the Brazilian method for developing subsets: use of specialized nursing language terms, construction of diagnostic statements and content validation of the statements by 40 specialist nurses. Those with a Content Validity Index (CVI) ≥ 0.

Determination of pesticide residue in marginal lagoons of natural parks in Brazil using an improved calibrate passive sampler.

Passive sampling is a sensitive and efficient method for analyzing pesticides in water. This article describes a hollow fiber liquid-phase microextraction (HF-LPME) device that was improved using polypropylene membranes grafted with nanocellulose for the passive sampling of pesticides in water. A comprehensive gas chromatography time-of-flight mass spectrometry (GCxGC/Q-TOFMS) system was used to separate, identify, and quantify pesticides.

Impact of exposure to atmospheric particulate matter in human skin-derived fibroblast cells: A metabolomics approach for the class of amino acids based on GC×GC-Q-TOFMS/MS.

The particulate matter (PM) in the air comprises particles containing a complex mixture of pollutants associated with various environmental and public health disturbances. However, studies related to the effects of PM on the skin are still incipient. In this work, the toxicity of particulate material to fibroblast cells derived from the human dermis was investigated using metabolomic analysis for the class of amino acids.

Effects of bisphenol A on murine salivary glands and human tumor cell lines.

Bisphenol A (BPA) is an endocrine-disrupting chemical with a potential role in endocrine cancers. However, the effects of BPA on the salivary glands have been barely explored. We investigated the impact of in vivo sub-chronic exposure to BPA and its in vitro effects on human salivary gland mucoepidermoid carcinoma cell lines.

Rapid and Accurate Prediction of the Axial Magnetic Anisotropy in Cobalt(II) Complexes Using a Machine-Learning Approach.

Estimating the magnetic anisotropy for single-ion magnets is complex due to its multireference nature. This study demonstrates that deep neural networks (DNNs) can provide accurate axial magnetic anisotropy () values, closely matching the complete-active-space self-consistent-field (CASSCF) quality using density functional theory (DFT) data. We curated an 86-parameter database (UFF1) with electronic data from over 33000 cobalt(II) compounds.

A Culex quinquefasciatus strain resistant to the binary toxin from Lysinibacillus sphaericus displays altered enzyme activities and energy reserves.

Background: The resistance of a Culex quinquefasciatus strain to the binary (Bin) larvicidal toxin from Lysinibacillus sphaericus is due to the lack of expression of the toxin's receptors, the membrane-bound Cqm1 α-glucosidases. A previous transcriptomic profile of the resistant larvae showed differentially expressed genes coding Cqm1, lipases, proteases and other genes involved in lipid and carbohydrate metabolism. This study aimed to investigate the metabolic features of Bin-resistant individuals by comparing the activity of some enzymes, energy reserves, fertility and fecundity to a susceptible strain.

A deep learning-based simulator for comprehensive two-dimensional GC applications.

Among the main approaches for predicting the spatial positions of eluates in comprehensive two-dimensional gas chromatography, the still under-explored computational models based on deep learning algorithms emerge as robust and reliable options due to their high adaptability to the structure and complexity of the data. In this work, an open-source program based on deep neural networks was developed to optimize chromatographic methods and simulate operating conditions outside the laboratory. The deep neural networks models were fit to convenient experimental predictors, resulting in scaled losses (mean squared error) equivalent to 0.

Evaluation of amino acid profile by targeted metabolomics in the eukaryotic model under exposure of benzo[a]pyrene as the exclusive stressor.

Amino acids (AAs) are a class of important metabolites in metabolomics methodology that investigates metabolite changes in a cell, tissue, or organism for early diagnosis of diseases. Benzo[a]pyrene (BaP) is considered a priority contaminant by different environmental control agencies because it is a proven carcinogenic compound for humans. Therefore, it is important to evaluate the BaP interference in the metabolism of amino acids.

Trends and Self-Management Predictors of Glycemic Control During Pregnancy in Women With Preexisting Type 1 or Type 2 Diabetes: A Cohort Study.

Background: Because much of diabetes management during pregnancy occurs at home, self-management factors such as self-efficacy, self-care activities, and care satisfaction may affect glycemia. Our objective was to explore trends in glycemic control during pregnancy in women with type 1 or type 2 diabetes; assess self-efficacy, self-care, and care satisfaction; and examine these factors as predictors of glycemic control.

Methods: We conducted a cohort study from April 2014 to November 2019 at a tertiary center in Ontario, Canada.