Novel Gene Variants in a Nationwide Cohort of Patients with Pheochromocytoma and Paraganglioma.

Pheochromocytomas (PCCs) and paragangliomas (PGLs), denoted PPGLs, are rare neuroendocrine tumours and are highly heterogeneous. The phenotype-genotype correlation is poor; therefore, additional studies are needed to understand their pathogenesis. We describe the clinical characteristics of 63 patients with PPGLs and perform a genetic study.

The Phylogenomic Characterization of Species and Their Cellulases for Biotechnological Applications.

This study aims to evaluate the in silico genomic characteristics of five species of the genus : , , , , and , with a view to their application in therapeutic research. The 16S rRNA comparison indicated that these species were phylogenetically distinct. Pairwise comparisons of digital DNA-DNA hybridization (dDDH) and OrthoANI values between these studied type strains indicated that dDDH values were below 62.

IFEM model curriculum: emergency medicine learning outcomes for undergraduate medical education.

Background: The International Federation for Emergency Medicine (IFEM) published its model curriculum for medical student education in emergency medicine in 2009. Because of the evolving principles of emergency medicine and medical education, driven by societal, professional, and educational developments, there was a need for an update on IFEM recommendations. The main objective of the update process was creating Intended Learning Outcomes (ILOs) and providing tier-based recommendations.

Reclassification of type strains of and into the species and , respectively.

The species and were isolated from legume nodules and the 16S rRNA sequences of their respective type strains, CCBAU 71042 and CCBAU 71714, were highly divergent from those of the other species of the genera and , respectively. However, the 16S rRNA gene sequences obtained for strains CCBAU 71042 and CCBAU 71714 several years after description, were different from the original ones, showing 100 % similarity to the type strains of and , respectively. Phylogenetic analyses of two housekeeping genes, and , confirmed the high phylogenetic closeness of strains CCBAU 71042 and CCBAU 71714 to the respective type strains of and .

Tailoring Fibroblast-Activation Protein Targeting for Theranostics: A Comparative Preclinical Evaluation of the Ga- and Lu-Labeled Monomeric and Dimeric Fibroblast-Activation Protein Inhibitors DOTA.SA.FAPi and DOTAGA.(SA.FAPi).

Background: FAP radiopharmaceuticals show promise for cancer diagnosis; however, their limited tumor residency hinders treatment. This study compared two FAPi derivatives, DOTA.SA.

[Hegemonies, subalternities, and possible counter-hegemonies: The case of traditional medicine of Indigenous peoples in Mexico].

A whole series of processes lead to the decrease in the use of traditional medicine by the indigenous peoples of Mexico, including the reduction in the number of traditional healers and the direct and indirect expansion of biomedicine. This essay addresses the central role these processes play in the relations of hegemony/subalternity that occur in different fields of reality, and especially in the health-illness-care-prevention processes, given that counter-hegemonic processes are not generated, or those that do arise have been ineffective in confronting social hegemony in general and biomedical hegemony in particular.

Carbonation Resistance of Ternary Portland Cements Made with Silica Fume and Limestone.

Ternary blended cements, made with silica fume and limestone, provide significant benefits such as improved compressive strength, chloride penetration resistance, sulfates attack, etc. Furthermore, they could be considered low-carbon cements, and they contribute to reducing the depletion of natural resources in reference to water usage, fossil fuel consumption, and mining. Limestone (10%, 15%, and 20%) with different fineness and coarse silica fume (3%, 5%, and 7%) was used to produce ternary cements.

β-Lactam allergy delabeling is safe and saves costs in Primary Care.

Objective: To determine whether the β-lactam allergy delabeling was safe and cost-saving in Primary Care (PC) patients.

Design: We have conducted a retrospective chart review of PC patients with β-lactam allergy label evaluated in our Allergy Unit between 2017 and 2022. SITE: Allergy Department.

Metabolic and Clinical Outcomes in Type 1 Diabetes in the COVID-19 Pre- and Post-Vaccination Periods in Spain: The COVID-SED1 Study.

To evaluate the metabolic and clinical outcomes in the Spanish type 1 diabetes mellitus (T1D) population before and after COVID-19 vaccination. A retrospective observational study was carried out in Spanish public hospitals previously enrolled in the SED1 study. Adults and children with T1D were included and their clinical electronic records were reviewed.

Integrating Egocentric and Robotic Vision for Object Identification Using Siamese Networks and Superquadric Estimations in Partial Occlusion Scenarios.

This paper introduces a novel method that enables robots to identify objects based on user gaze, tracked via eye-tracking glasses. This is achieved without prior knowledge of the objects' categories or their locations and without external markers. The method integrates a two-part system: a category-agnostic object shape and pose estimator using superquadrics and Siamese networks.

Reversible optical control of magnetism in engineered artificial multiferroics.

Optical means instead of electric fields may offer a new pathway for low-power and wireless control of magnetism, holding great potential to design next-generation memory and spintronic devices. Artificial multiferroic materials have shown remarkable suitability as platforms towards the optical control of magnetic properties. However, the practical use of magnetic modulation should be both stable and reversible and, particularly, it should occur at room temperature.

Juvenile Plant-Microbe Interactions Modulate the Adaptation and Response of Forest Seedlings to Rapid Climate Change.

The negative impacts of climate change on native forest ecosystems have created challenging conditions for the sustainability of natural forest regeneration. These challenges arise primarily from abiotic stresses that affect the early stages of forest tree development. While there is extensive evidence on the diversity of juvenile microbial symbioses in agricultural and fruit crops, there is a notable lack of reports on native forest plants.

[On specialized oversights: biomedicine as an intrinsic part of life for indigenous peoples].

The vast majority of studies on traditional medicine disregard the existence of biomedicine and alternative and complementary medicines in the lives of the indigenous peoples of Mexico and Latin America in general, despite the fact that these populations increasingly make use of biomedical knowledge more and more intensively. In this text I have attempted to elucidate this expansion of biomedicine and the decline of traditional medicine, through ethnographic information related to different indigenous groups. This expansion of biomedicine takes place despite the various negative consequences it generates due to different factors such as its comparative effectiveness, which is evidenced in the use of and demand for pharmaceuticals, biomedical services, and in particular the construction of hospitals in their communities.

Wireless magneto-ionics: voltage control of magnetism by bipolar electrochemistry.

Modulation of magnetic properties through voltage-driven ion motion and redox processes, i.e., magneto-ionics, is a unique approach to control magnetism with electric field for low-power memory and spintronic applications.

Association between exposure to air pollution and blood lipids in the general population of Spain.

Background And Aims: We aimed to assess the associations of exposure to air pollutants and standard and advanced lipoprotein measures, in a nationwide sample representative of the adult population of Spain.

Methods: We included 4647 adults (>18 years), participants in the national, cross-sectional, population-based di@bet.es study, conducted in 2008-2010.

Physical activity patterns in type 1 diabetes in Spain: The SED1 study.

Aims: To describe the physical activity (PA) frequency and intensity in the Spanish type 1 diabetes mellitus (T1D) population and its association with their glycemic control.

Methods: A cross-sectional observational study was carried out in 75 Spanish public hospitals (the SED1 study). T1D patients over 14years of age self-completed the International Physical Activity Questionnaire (IPAQ) to determine their level of exercise.

[Some memories and possible oversights of my anthropological trajectory].

This text is a transcription of the speech delivered by Eduardo L. Menéndez at the ceremony in which he was conferred a Doctorate Honoris Causa by the Universidad Nacional de Lanús on March 27, 2023. The speech covers aspects of his youth and academic career in Argentina, prior to his exile in Mexico in 1976, and reflects on various processes that due to a number of circumstances consciously or unconsciously oriented his field of inquiry and contextualize his theoretical contributions.

Translational assessment of a DATA-functionalized FAP inhibitor with facile Ga-labeling at room temperature.

Purpose: The present study aims at evaluating the preclinical and the clinical performance of [Ga]Ga-DATASA.FAPi, which has the advantage to be labeled with gallium-68 at room temperature.

Methods: [Ga]Ga-DATA.

Complete Genome Sequences of the Species Type Strains Sinorhizobium garamanticum LMG 24692 and Sinorhizobium numidicum LMG 27395 and CIP 109850.

The genus comprises rhizobia that fix nitrogen in symbiosis with legumes. To support taxonomic studies of this genus and of rhizobia more broadly, we report complete genome sequences and annotations for the species type strains Sinorhizobium garamanticum LMG 24692 and Sinorhizobium numidicum LMG 27395 and CIP 109850.

Regulating Oxygen Ion Transport at the Nanoscale to Enable Highly Cyclable Magneto-Ionic Control of Magnetism.

Magneto-ionics refers to the control of magnetic properties of materials through voltage-driven ion motion. To generate effective electric fields, either solid or liquid electrolytes are utilized, which also serve as ion reservoirs. Thin solid electrolytes have difficulties in (i) withstanding high electric fields without electric pinholes and (ii) maintaining stable ion transport during long-term actuation.

The Guadalajara Declaration on sepsis: emergency physicians' constructive comments on the Surviving Sepsis Campaign's 2021 updated guidelines.

The Surviving Sepsis Campaign (SSC) published a 2021 update of its 2016 recommendations. The update was awaited with great anticipation the world over, especially by emergency physicians. Under the framework of the CIMU 2022 (33rd World Emergency Medicine Conference) in Guadalajara, Mexico in March, emergency physiciansreviewed and analyzed the 2021 SSC guidelines from our specialty's point of view.

[The origins and development of traditional medicine: an ideological issue].

Most analysts identify three main foundations of the development of traditional Mexican medicine between the 15th and 18th centuries (pre-Hispanic, Hispanic, and African), as well as a number of complementary sources incorporated over the course of the 18th and 19th centuries. However, a significant proportion of leading specialists consider pre-Hispanic medicine to be the primary basis of traditional medicine, downplaying Hispanic influence and disregarding African influence. Furthermore, they either ignore or give only cursory treatment to the role of biomedicine in the present-day medicalization of traditional medicine.