Publications by authors named "Mendez-Bailon M"

Introduction: Transthyretin cardiac amyloidosis is a pathology increasingly encountered in all hospital departments, including internal medicine. The aim of our study is to describe the characteristics and care pathway of patients with transthyretin cardiac amyloidosis in internal medicine and to show that the number of patients diagnosed is increasing.

Methods: Descriptive, retrospective, non-interventional, single-center study at Strasbourg University Hospitals (HUS).

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Unlabelled: Type 2 diabetes is a public health problem in which general practitioners are in the front line, acting on all fronts, from screening to management.

Methods: Single-centre, quantitative, retrospective and descriptive study aimed at characterising the profile of patients referred to hospital by general practitioners in an internal medicine department in Strasbourg for rebalancing of their type 2 diabetes during the period from 1 January 2020 to 31 December 2022.

Results: 167 files were analysed, resulting in the inclusion of 72 patients with an average age of 61.

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Introduction: Patients with heart failure in sinus rhythm may be at significant risk of major cardiovascular events, including cardiovascular death (CV death).

Objective: To assess CV mortality at a one-year follow up of those patients with heart failure and sinus rhythm, according to LVEF subgroups.

Methods: A prospective and multicentric study was conducted with patients in sinus rhythm included in the National Registry of Heart Failure.

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Background: Patients with heart failure (HF) and chronic obstructive pulmonary disease (COPD) have a high risk of hospital admission and mortality. This study evaluated the benefit of a care model, characterized by comprehensive and continuous care (UMIPIC program) in patients with HF and a history of COPD.

Methods: A total of 5644 patients were prospectively recruited, of which 1320 had a history of COPD between March 2008 and March 2020.

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Aims: To design a strategic framework for the policy and activity of the Spanish Society of Internal Medicine (SEMI).

Methods: Expert consensus. Participation through expert committees and consultation of internists on the proposed strategic lines.

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Article Synopsis
  • Sarcopenia, or low muscle strength, is a significant comorbidity in patients with acute heart failure (AHF), potentially worsening their prognosis, leading researchers to study its impact on these patients.
  • The study analyzed 377 AHF patients and found that 82.23% had low muscle strength, which was associated with older age, cognitive impairment, and poorer functional status.
  • Results indicated that patients with low muscle strength had higher rates of readmission and mortality, reinforcing the link between low muscle strength and worse outcomes in AHF.
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Article Synopsis
  • * Certain populations, like newborns, pregnant women, and the elderly, are more susceptible to deficiencies, especially those with digestive or chronic health issues.
  • * Symptoms of deficiencies can lead to specific health problems; treatment involves vitamin supplementation and addressing dietary or health-related causes.
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Article Synopsis
  • Heart failure (HF) is a common and serious condition, especially in older adults, leading to many hospital admissions, with acute heart failure (AHF) as a primary diagnosis.
  • Sodium-glucose cotransporter type 2 inhibitors (SGLT2is) can enhance survival and quality of life for HF patients, and this study aimed to evaluate their effects on readmission and mortality rates.
  • In a study involving 750 patients, only 28% were treated with SGLT2is; those who received the medication were generally younger and had lower left ventricular ejection fractions, and they experienced lower mortality during their hospital admission.
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Introduction: Patients with heart failure (HF) are known to have an increased risk of pulmonary embolism (PE), but there is limited evidence regarding the prognostic implications of HF in patients with acute PE and the relationship between PE prognosis and left ventricular ejection fraction (LVEF). The primary objective of this study was the development of a composite outcome (mortality, major bleeding, and recurrence) within the first 30 days. The secondary objective was to identify the role of LVEF in predicting the development of early complications in patients with both HF and reduced LVEF.

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Introduction: Given the increasing adoption of clinical ultrasound in medicine, it is essential to standardize its application, training, and research.

Objectives And Methods: The purpose of this document is to provide consensus recommendations to address questions about the practice and operation of clinical ultrasound units. Nineteen experts and leaders from advanced clinical ultrasound units participated.

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Polymyalgia rheumatica and giant cell arteritis can be a medical emergency in which a delay in correct diagnosis and therapeutic management can cause serious complications. With the aim of improving the care of patients with these pathologies in the Community of Madrid, a study was designed to identify the causes and possible solutions to address the problems related to the diagnosis of these pathologies. After the analysis, 11 areas of improvement related to four different aspects of the care process were identified: coordination and protocols, equipment, training and awareness of pathologies, and patient experience.

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Article Synopsis
  • Patients with heart failure (HF) and cardiorenal syndrome (CRS) face challenges like higher hospital stays and mortality rates due to their age and health issues.
  • The UMIPIC program, involving specialized care from internists and nurses, was studied to see if it could improve outcomes for these patients.
  • Results showed that those in the UMIPIC program had significantly fewer hospital readmissions (20% vs 32%) and lower mortality rates (24% vs 36%) compared to those receiving standard care, indicating its effectiveness in providing better long-term management.
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Background: Patients with chronic diseases such as heart failure (HF) are at risk of hospital admission. We evaluated the impact of living in nursing homes (NH) on readmissions and all-cause mortality of HF patients during a one-year follow up.

Methods: An observational and multicenter study from the Spanish National Registry of Heart Failure (RICA) was performed.

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Article Synopsis
  • The study analyzed COVID-19 hospital admissions from 2020 in Spain, focusing on older patients during two pandemic waves, to evaluate mortality differences.
  • Results showed a mortality rate of 20.4% during the first wave and 17.2% during the second wave, particularly among patients aged 70 and older, who had a significant mortality reduction of 7.6%.
  • The lower mortality in the second wave may be due to improved healthcare standards, greater clinical experience, or less strain on the healthcare system, independent of patient or disease severity.
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Background: Most patients diagnosed with heart failure (HF) are older adults with multiple comorbidities. Multipathological patients constitute a population with common characteristics: greater clinical complexity and vulnerability, frailty, mortality, functional deterioration, polypharmacy, and poorer health-related quality of life with more dependency.

Objectives: To evaluate the clinical characteristics of hospitalized patients with acute heart failure and to determine the prognosis of patients with acute heart failure according to the Short Physical Performance Battery (SPPB) scale.

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Introduction: Patients with diabetes mellitus (DM) and heart failure (HF) have a worse prognosis despite therapeutic advances in both diseases. Sodium-glucose co-transporter type 2 and GLP-1 receptor agonists have shown cardiovascular benefits and they have been positioned as the first step in the treatment of DM in patients with HF or high cardiovascular risk. However, in the pivotal trials the majority of patients receive concomitant treatment with metformin.

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Article Synopsis
  • - The study investigates the relationship between COVID-19 and heart failure (HF), focusing on identifying risk factors for HF among hospitalized COVID-19 patients in Spain.
  • - A total of 16,474 patients were analyzed, with 5.8% developing HF; significant risk factors included older age, atrial fibrillation, obesity, and peripheral vascular disease.
  • - Patients who developed HF had notably higher mortality rates, increased need for intubation, and higher ICU admission rates compared to those who did not develop HF.
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Heart failure is a disease with an increasingly greater prevalence due to the aging population, the development of new drugs, and the organization of healthcare processes. Malnutrition has been identified as a poor prognostic factor in these patients, very often linked to frailty or to other comorbidities, meaning that early diagnosis and treatment are essential. This paper reviews some important aspects of the pathophysiology, detection, and management of malnutrition in patients with heart failure.

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Atrial fibrillation (AF) is the most common arrhythmia in adults and diabetes mellitus (DM) is a major risk factor for cardiovascular diseases. However, the relationship between both pathologies has not been fully documented and new evidence supports the existence of direct and independent links. In the myocardium, a combination of structural, electrical, and autonomic remodeling may lead to AF.

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  • Sacubitril-valsartan has been shown to lower hospitalizations and death rates in heart failure patients, but there is limited real-world data on its effectiveness in older patients.
  • A study was conducted using a Spanish heart failure registry to compare elderly patients treated with sacubitril-valsartan versus those on angiotensin converting enzyme inhibitors (ACEI) during acute heart failure hospitalization.
  • Results indicated that while sacubitril-valsartan was associated with a trend towards fewer readmissions and deaths due to heart failure compared to ACEI, these findings were not statistically significant over follow-up periods of 3 months and 1 year.
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Diabetic foot is a complex disease. One of its most important complications is infection with risk of limb loss. In severe cases it is also a life-threatening condition.

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Introduction: Atrial fibrillation and associated comorbidities pose a risk factor for mortality, morbidity and development of complications in patients admitted for COVID-19.

Objectives: To describe the clinical, epidemiological, radiological and analytical characteristics of patients with AF admitted for COVID-19 in Spain. Secondarily, we aim to identify those variables associated with mortality and poor prognosis of COVID-19 in patients with AF.

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