Publications by authors named "Menashe M Bar-Eli"
J Natl Cancer Inst
March 2008
Article Synopsis
- IL-8 is a proangiogenic cytokine often found at high levels in ovarian cancer, linked to more advanced disease, higher tumor grades, and worse patient survival.
- Research involved testing the effects of silencing IL-8 in mouse models of ovarian cancer, showing that using IL-8 siRNA in combination with the chemotherapy drug docetaxel significantly reduced tumor growth and microvessel density.
- The results suggest that targeting IL-8 could improve treatment outcomes for ovarian cancer patients, especially in those resistant to traditional therapies.
