The study explored the differences in volatile organic compounds (VOCs) from the feces of rats treated with Baihe Jizihuang Tang (BHT) in a depression model induced by chronic stress, using advanced analysis techniques.
Eleven specific biomarkers were identified through various statistical methods, showcasing the potential therapeutic effects of traditional Chinese medicine (TCM) in treating complex diseases.
The research demonstrated the effectiveness of using headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) for quickly identifying clinical biomarkers without extensive sample preparation, supporting its application in future studies.