Publications by authors named "Melvin Mensah-Bonsu"
Article Synopsis
- The study investigates the factors influencing outcomes of Ebola virus disease, focusing on differences between fatal cases and survivors compared to healthy individuals.
- Researchers identified a significant number of differentially expressed genes (DEGs), revealing 13,198 DEGs in those who died and 12,039 in survivors, with specific hub genes linked to critical biological processes like immune response and blood coagulation.
- The findings suggest unique genetic markers for fatal and survival outcomes, which could enhance understanding of Ebola pathogenesis and inform targeted treatment strategies for the disease.
Ebola virus (EBOV) is a highly pathogenic virus that causes a severe illness called Ebola virus disease (EVD). EVD has a high mortality rate and remains a significant threat to public health. Research on EVD pathogenesis has traditionally focused on host transcriptional responses.
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