Publications by authors named "Melville J Da Cruz"

Article Synopsis
  • The supplementary data relates to a study on a novel suprachoroidal visual prosthesis implanted in sheep, assessing surgical safety, device stability, and biocompatibility.
  • Nine sheep underwent surgery with an electrically inactive retinal stimulator, monitored for up to 100 days through various imaging techniques.
  • The collected data, including images and histological analysis, serves as a reference for future research, particularly concerning active retinal stimulators and the suitability of Dorper sheep as research models.
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Severe visual impairment can result from retinal degenerative diseases such as retinitis pigmentosa, which lead to photoreceptor cell death. These pathologies result in extensive neural and glial remodelling, with survival of excitable retinal neurons that can be electrically stimulated to elicit visual percepts and restore a form of useful vision. The Phoenix Bionic Eye is a fully implantable visual prosthesis, designed to stimulate the retina from the suprachoroidal space.

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Background: Traditional tympanoplasty techniques require graft placement and then supporting material (GelFoam) as a two-step process. Both steps potentially disrupt accurate graft placement leading to failure and persistence of the perforation.

Methods: We demonstrate a novel technique for graft preparation and placement using composite gelfoam/fascia in which the gelfoam and fascia are compressed into a common layer and applied to the perforation and drum remnant in a single step.

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Objective: The purpose of this study was to characterize a cohort of patients with nonauditory side-effects (NASx) following cochlear implant (CI) surgery.

Study Design: Retrospective case review.

Setting: Tertiary referral center.

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Hypothesis: Three-dimensional (3D) printed temporal bones are comparable to cadaveric temporal bones as a training tool for otologic surgery.

Background: Cadaveric temporal bone dissection is an integral part of otology surgical training. Unfortunately, availability of cadaveric temporal bones is becoming much more limited and concern regarding chemical and biological risks persist.

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Unlabelled: : Developing a clinically viable technique for measuring cochlear length could enhance future electrode design of cochlear implants and surgical skills to improve clinical outcomes. While computed tomography (CT) has been used, metal artifact and the exposure to higher levels of radiation limits its use. More recently, cone beam CT (CBCT) has been used to assess the integrity of the implant array in situ, exposing implantees to lower levels of radiation while retaining image quality.

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Background: The infratemporal fossa is a well-concealed, complex anatomical space. Neoplasms arising in this area are heterogenous in nature and have an insidious onset and usually present late.

Methods And Results: We present a case of a 71-year-old woman who presented with worsening facial pain, trismus, and a large mass in her infratemporal fossa with minimal associated temporomandibular joint destruction.

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Osteogenesis imperfecta (OI) is a disorder of bone development caused by a genetic dysfunction of collagen synthesis. Basilar invagination (BI) is an uncommon but serious complication of OI. Brainstem decompression in OI is undertaken in certain circumstances.

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