Effect of dexamethasone therapy in Crimean-Congo hemorrhagic fever in Giresun during 2021-2023: an analytical study.

Background Objectives: Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic disease and significant health concern particularly in endemic regions. We aimed to evaluate the efficacy in dexamethasone treatment on clinical outcomes in CCHF patients.

Methods: We included adult patients diagnosed with CCHF and those whose platelet count dropped to 70,000/mm3 or lower.

The role of clinical and laboratory finding in the differential diagnosis of Hantavirus and Leptospirosis infections.

Background Objectives: Hantavirus and leptospirosis infections are zoonotic diseases with similar clinical and laboratory findings. The aim of this study is identifying the distinguishing features of these two diseases, for which a definitive diagnosis can take a long time.

Methods: Between September 2021 and June 2023, a total of 45 patients who were admitted to our hospital and were diagnosed with HFRS or leptospirosis were retrospectively evaluated.

Gastrointestinal PCR panel results and antibiotic use in acute gastroenteritis cases: How appropriate are we in our usage?

Background: We aimed to determine the pathogens detected by the Gastrointestinal (GI) PCR panel in patients with acute gastroenteritis (AGE), the evaluation of antibiotic use in these patients, and the investigation of the role of laboratory parameters in differentiating viral and bacterial etiologies.

Methods: The demographic characteristics, GI PCR panel results, laboratory investigations, antibiotic usage, and appropriateness of antibiotic treatment were investigated in AGE patients.

Results: A total of 175 adult patients with AGE and GI PCR panel results were included in the study.

Evaluation of the implementation of WHO infection prevention and control core components in Turkish health care facilities: results from a WHO infection prevention and control assessment framework (IPCAF)-based survey.

Background: The core components (CCs) of infection prevention and control (IPC) from World Health Organization (WHO) are crucial for the safety and quality of health care. Our objective was to examine the level of implementation of WHO infection prevention and control core components (IPC CC) in a developing country. We also aimed to evaluate health care-associated infections (HAIs) and antimicrobial resistance (AMR) in intensive care units (ICUs) in association with implemented IPC CCs.

Analysis of epidemiology and risk factors for mortality in ventilator-associated pneumonia attacks in intensive care unit patients.

Background/aim: The aim of this study was to investigate the epidemiologic characteristics, the causative microorganisms and their antimicrobial susceptibility patterns, and the prognostic risk factors for mortality in critically ill patients with ventilator-associated pneumonia (VAP).

Materials And Methods: In this retrospective observational study, all the critically ill patients with VAP hospitalized in a medical/surgical intensive care unit (ICU) between January 2010 and June 2015 were evaluated. Patients' demographic features and microbiological data were reviewed.

Investigating the in vitro synergistic activities of several antibiotic combinationsagainst carbapenem-resistant Acinetobacter baumannii isolates.

Background/aim: Acinetobacter baumannii (A. baumannii) is one of the most common healthcare-associated infectious agents worldwide. The aim of this study was to investigate the in vitro synergistic activities of several antibiotic combinations against carbapenem-resistant (CR) A.

Does the course of laboratory parameters help us to predict the outcome of CCHF?

Background/aim: This study was performed to identify the characteristics distinguishing fatal and nonfatal cases of patients diagnosed with Crimean-Congo hemorrhagic fever (CCHF).

Materials And Methods: A total of 92 patients with confirmed diagnosis of CCHF in 2009-2013 were included in the study.

Results: A high level of urea and aPTT on the third day of hospital stay, diarrhea, somnolence, and the interval from the beginning of the symptoms to hospital admission were independently associated with fatality.

Mortality predictors of Staphylococcus aureus bacteremia: a prospective multicenter study.

Background: Staphylococcus aureus is one of the causes of both community and healthcare-associated bacteremia. The attributable mortality of S. aureus bacteremia (SAB) is still higher and predictors for mortality and clinical outcomes of this condition are need to be clarified.

A long-term survey of brucellosis: Is there any marker to predict the complicated cases?

Background: This study aimed to find markers to predict complicated cases in brucellosis. Patients with and without complications were compared in terms of epidemiological, clinical and laboratory properties.

Methods: A total of 700 patients hospitalised at the Department of Infectious Diseases and Clinical Microbiology were evaluated retrospectively.

Emergence of multidrug resistant isolates and mortality predictors in patients with solid tumors or hematological malignancies.

Introduction: Infections are an important preventable cause of death in cancer patients. The aim of this study was to clarify the epidemiologic characteristics and resistance patterns of causative isolates and mortality predictors in infections of cancer patients.

Methodology: Patients with sterile site infections were evaluated in a retrospective cohort study.

Crimean-Congo Hemorrhagic Fever: Prognostic Factors and the Association of Leukocyte Counts with Mortality.

We aimed to determine the relationship between leukocyte counts and the survival of patients with Crimean-Congo hemorrhagic fever (CCHF), a life-threatening illness. This is the first study to do so. A total of 220 patients with CCHF were evaluated retrospectively.

A case of Crimean-Congo hemorrhagic fever complicated with acute pancreatitis.

Background: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease characterized by nonspecific symptoms like fever, myalgia, severe headache, nausea, vomiting, diarrhea, and abdominal pain. It can result in various complications during the course of the disease due to the diffuse endothelial injury involved in the pathogenesis of CCHF.

Objectives: Here we present a patient with CCHF complicated by acute pancreatitis, including pleural and intra-abdominal effusions.

[Evaluation of Candida colonization in intensive care unit patients and the use of Candida colonization index].

Parallel to the developments in the field of diagnosis and treatment, an increase in the incidence of fungal infections and the number of patients who are in the risk group for the development of opportunistic fungal infections have been observed in the recent years. Among the hospitalized patients, those most at risk in terms of fungal infections are intensive care unit (ICU) patients. The rate of Candida colonization of mucous membranes in hospitalized patients may reach to 80%, and this may predispose to the establishment of severe infections especially in patients under risk.

Evaluation of clinical and laboratory predictors of fatality in patients with Crimean-Congo haemorrhagic fever in a tertiary care hospital in Turkey.

The fatality rate of Crimean-Congo haemorrhagic fever (CCHF) disease has been reported as 5.4-80%. In this prospective study our aim was to evaluate the clinical and laboratory predictors of fatality in patients with CCHF.

[Comparison of the diagnostic value of blood and bone marrow cultures in brucellosis].

The aim of this study was to compare the rates of brucellosis revealed by blood and bone marrow (BM) cultures obtained from patients followed up in our hospital, between 2002-2004 period. A total of 102 patients (62 male, 40 female; mean age: 39 +/- 5 years) were included to the study and 61 of them were in acute, 29 were in subacute, and 12 were in chronic stages of brucellosis. Blood and BM samples collected from all of the hospitalized patients were cultured by using the BACTEC 9050 system.

Evaluation of the clinical presentations in neurobrucellosis.

Background: Brucellosis is a multisystem disease that may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is one of the complications.

Methods: In this study, we describe our experience in the diagnosis, treatment, and the final outcomes of 20 patients with neurobrucellosis out of 305 patients with brucellosis, within a five-year period between January 1999 and June 2004.

Epididymoorchitis due to brucellosis in central Anatolia, Turkey.

Brucellosis may involve many organs and tissues. Epididymoorchitis is a focal genitourinary complication of human brucellosis. In this study, we describe our experience with the diagnosis, treatment, and final outcomes of 17 patients with epididymoorchitis out of 186 male patients with brucellosis between March 1999 and December 2003.