Publications by authors named "Mellisa Mei Hui Tan"
Purpose: To investigate the associations of Single Nucleotide Polymorphisms (SNPs) in the SNTB1 gene with high myopia in a Han Chinese population.
Materials And Methods: Based on previous studies, four SNPs from the SNTB1 gene were chosen for genotyping. This is a case-control genetic association study comprising 193 high myopia participants and 135 normal emmetropic controls from a Han Chinese population.
Purpose: To describe visual performance in high myopia.
Methods: In this cross-sectional study, 148 emmetropes [spherical equivalent (SE) - 0.50 to + 1.
Refractive outcomes, corneal haze and endothelial cell loss after myopic photorefractive keratectomy in an Asian population: The Singapore Armed Forces' experience.
Clin Exp Ophthalmol
July 2020
Importance: This study reports outcomes of myopic photorefractive keratectomy (PRK) in a mainly ethnic Chinese population in Singapore.
Background: To assess the incidence and associations of corneal haze and endothelial cell count (ECC) loss up to 12 months after PRK.
Design: This was a retrospective case series conducted in a tertiary eye centre.
Article Synopsis
- A study explored the connection between specific Single Nucleotide Polymorphisms (SNPs) in the VIPR2 and ZMAT4 genes and high myopia in a Han Chinese population, using 193 myopia patients and 135 normal controls.
- Two SNPs, RS885863 and RS7829127, were found to have significant associations with high myopia, affecting the odds ratio and axial length of the eye.
- The results suggest that these SNPs play a critical role in the genetic predisposition to high myopia, pointing towards their potential importance in future genetic studies and myopia research.
Risk factors for early-onset corneal haze after photorefractive keratectomy in an Asian population: Outcomes from the Singapore Armed Forces Corneal Refractive Surgery Programme 2006 to 2013.
J Cataract Refract Surg
May 2016
Purpose: To assess the incidence and risk factors for early corneal haze after myopic photorefractive keratectomy (PRK).
Setting: Tertiary eye center, Singapore.
Design: Retrospective case series.
Purpose: To determine the differences in prevalence rates of refractive errors in young Singaporean males over a 13-year period between 1996-1997 and 2009-2010 METHODS: Non-cycloplegic autorefraction data were obtained in a survey of 15,085 young male subjects (mean age 19.5 ± 1.4 years, range 16-25 years) in 1996-1997 using a Nikon NRK-8000 autorefractor.
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