Introduction: Knowledge about the energy expenditure of typical activities of daily living (ADL) in persons with lower limb amputation (LLA) is lacking. This study investigated the following: (1) oxygen consumption per unit distance (V̇O 2 ; mL·kg -1 ·min -1 ), (2) proportion utilization of peak oxygen consumption (%V̇O 2 peak), (3) oxygen cost (energy cost; mL·kg -1 ·m -1 ), and (4) perceived exertion (rating of perceived exertion) of ADL in persons with LLA and able-bodied controls.
Methods: Participants (21 with LLA/12 controls) performed 2 household ADL experiments: in-house walking and vacuuming and 3 community ADL experiments: marked shopping, fast walking, and stair negotiation.
Background: This study investigated the impact of COVID-19 restrictions on ambulatory activity and health-related quality of life (HR-QoL) in people with a lower limb amputation (LLA) in Norway. We hypothesized that the restrictions would negatively affect HR-QoL and decrease prosthetic wear time and ambulatory activity in participants with already limited mobility.
Methods: Twenty individuals with LLA (age and time since amputation 56.
Background: The rapidly increasing use of wearable technology to monitor free-living ambulatory behavior demands to address to what extent the chosen outcome measures are representative for real-world situations. This scoping review aims to provide an overview of the purpose of use of wearable activity monitors in people with a Lower Limb Amputation (LLA) in the real world, to identify the reported outcome measures, and to evaluate to what extent the reported outcome measures capture essential information from real-world ambulation of people with LLA.
Methods: The literature search included a search in three databases (MEDLINE, CINAHL, and EMBASE) for articles published between January 1999 and January 2022, and a hand-search.
The "mouthfeel" of food products is a key factor in our perception of food quality and in our appreciation of food products. Extensive research has been performed on what determines mouthfeel, and how it can be linked to laboratory measurements and eventually predicted. This was mainly done on the basis of simple models that do not accurately take the rheology of the food products into account.
View Article and Find Full Text PDFBackground: Previous studies show that people with lower limb amputation (LLA) have a sedentary lifestyle, reduced walking capacity, and low cardiorespiratory fitness (VO2peak). There is, however, no knowledge on the relationship between cardiorespiratory fitness and objectively measured level of physical activity in daily life.
Objectives: To investigate the relationship between upper-body VO2peak, physical activity levels, and walking capacity in persons with LLA.
To enhance prevention and treatment of malnutrition in older adults before, during and after hospitalization, deeper understanding of older adults' and informal caregivers' perspective on nutritional care is important. One-time in-depth interviews were conducted with 15 older adults who had been discharged from hospital, and seven informal caregivers. We explored their experiences and needs regarding nutritional care provided in the periods before, during and after hospitalization.
View Article and Find Full Text PDFPurpose: To compare the effects of test protocols with different increments in workload and duration on peak oxygen uptake ([Formula: see text]O), and related physiological parameters during seated upper-body poling (UBP).
Methods: Thirteen upper-body trained, male individuals completed four UBP test protocols with increments in workload until volitional exhaustion in a counterbalanced order: 20 W increase/every 30 s, 20 W/60 s, 10 W/30 s and 10 W/60 s. Cardio-respiratory parameters and power output were measured throughout the duration of each test.
OBJECTIVE To determine the most common types of injuries in cats surgically treated for thoracic trauma, complications associated with surgical treatment, and factors associated with mortality rate and evaluate the effectiveness of the animal trauma triage (ATT) scoring system for predicting outcome. DESIGN Retrospective case series with nested observational study. ANIMALS 23 client-owned cats surgically treated for thoracic trauma at 7 veterinary teaching hospitals between 1990 and 2014.
View Article and Find Full Text PDFOBJECTIVE To determine perioperative mortality rate and identify risk factors associated with outcome in dogs with thoracic trauma that underwent surgical procedures and to evaluate the utility of the animal trauma triage (ATT) score in predicting outcome. DESIGN Retrospective case series. ANIMALS 157 client-owned dogs.
View Article and Find Full Text PDFA novel treatment modality incorporating calcium-adhering microbubbles has recently entered human clinical trials as a new minimally-invasive approach to treat urinary stones. In this treatment method, lipid-shell gas-core microbubbles can be introduced into the urinary tract through a catheter. Lipid moities with calcium-adherance properties incorporated into the lipid shell facilitate binding to stones.
View Article and Find Full Text PDFUrinary stone disease, particularly calcium oxalate, is common in both humans and cats. Calcifying nanoparticles (CNP) are spherical nanocrystallite material, and are composed of proteins (fetuin, albumin) and inorganic minerals. CNP are suggested to play a role in a wide array of pathologic mineralization syndromes including urolithiasis.
View Article and Find Full Text PDFPierce's disease (PD) is a deadly disease of grapevines caused by the Gram-negative bacterium Xylella fastidiosa. Though disease symptoms were formerly attributed to bacteria blocking the plant xylem, this hypothesis is at best overly simplistic. Recently, we used a proteomic approach to characterize the secretome of X.
View Article and Find Full Text PDFObjective: To describe indications for, and outcomes after, pneumonectomy in dogs and cats, including assessment of immediate postoperative respiratory function in comparison to dogs undergoing single lung lobectomy.
Study Design: Retrospective case series.
Animals: Dogs (n=16) and cats (n=7) with naturally occurring pulmonary disease.
Mesenchymal stem cells (MSC) are known to facilitate healing of ischemic tissue related diseases through proangiogenic secretory proteins. Recent studies further show that MSC derived exosomes function as paracrine effectors of angiogenesis, however, the identity of which components of the exosome proteome responsible for this effect remains elusive. To address this we used high-resolution isoelectric focusing coupled liquid chromatography tandem mass spectrometry, an unbiased high throughput proteomics approach to comprehensively characterize the proteinaceous contents of MSCs and MSC derived exosomes.
View Article and Find Full Text PDFOne of the most common types of urinary stones formed in humans and some other mammals is composed of calcium oxalate in ordered hydrated crystals. Many studies have reported a range of metals other than calcium in human stones, but few have looked at stones from animal models such as the dog. Therefore, we determined the elemental profile of canine calcium oxalate urinary stones and compared it to reported values from human stones.
View Article and Find Full Text PDFObjectives: To determine if bulldogs develop a hypercoagulable state comparable to that observed in human patients with sleep apnoea hypopnoea syndrome.
Materials And Methods: Thromboelastography was performed in 15 clinically healthy bulldogs and 24 healthy control dogs of other breeds or mixed breed lineage.
Results: Bulldogs had significantly shorter R and K times relative to control dogs.
Objective: To compare the diagnostic performance of the traditional approach to acid-base analysis with the Stewart approach and a semiquantitative approach.
Design: Prospective cohort study.
Setting: University teaching hospital.
Objective: To compare the diagnostic performance of the anion gap (AG) with 2 physicochemical approaches to identify unmeasured anions.
Design: Prospective cohort study.
Setting: University teaching hospital.
J Vet Emerg Crit Care (San Antonio)
April 2015
Objective: To evaluate the effects of hetastarch 670/0.75 on canine platelet function and clinical bleeding following its administration as a constant rate infusion (CRI) at 1 mL/kg/h and 2 mL/kg/h for 24 hours.
Design: In vivo, prospective, open-label, crossover study.
Background: Brachycephalic dogs are at risk for arterial hypertension and obstructive sleep apnea, which are both associated with chronic magnesium (Mg) depletion.
Hypothesis/objectives: To compare the period prevalence of hypomagnesemia between Boxers and Bulldogs presented to a referral teaching hospital. To screen a group of Bulldogs for evidence of hypomagnesemia, and to obtain pilot data regarding the utility of parenteral Mg tolerance testing (PMgTT) in the diagnosis of whole-body Mg deficiency.
J Vet Emerg Crit Care (San Antonio)
December 2014
Objective: To determine the normal osmole gap for 18 previously published formulae used to estimate serum osmolality in dogs.
Design: Prospective study.
Setting: University veterinary medical teaching hospital.
J Vet Intern Med
September 2014
Background: Pericardial effusion cytology is believed by many to be of limited value, yet few studies have evaluated its diagnostic utility.
Objectives: To determine the diagnostic utility of cytologic analysis of pericardial effusion in dogs and to determine if consideration of additional data could improve the diagnostic yield.
Animals: Two hundred and fifty-nine dogs with cytologic analysis of pericardial effusion performed between April 1990 and June 2012.
Ventilator waveforms are graphic representations of changes in pressure, flow, and volume within a ventilator circuit. The changes in these parameters over time may be displayed individually (scalars) or plotted one against another (pressure-volume and flow-volume loops). There are 6 basic shapes of scalar waveforms, but only 3 are functionally distinct (square, ramp, and sine).
View Article and Find Full Text PDFJ Vet Intern Med
October 2014
Background: Pulmonary embolism (PE) is a complication of systemic disease in dogs. Antemortem diagnosis is challenging because of the lack of a confirmatory test.
Objectives: To retrospectively determine the diagnostic utility of D-dimer concentrations in dogs with necropsy-confirmed PE.
Objective: To determine the osmole gap utilizing 18 previously published formulae for the estimation of serum osmolality in cats.
Procedures: Serum samples were frozen at -80°C after routine biochemical analysis. An Advanced Micro Osmometer 3300 was used to measure serum osmolality.