Publications by authors named "Melissa van der Windt"

Background: A healthy lifestyle plays a key role in the prevention of lifestyle-related diseases, including subfertility and pregnancy complications. Although the benefits of a healthy lifestyle are well-known, long-term adherence is limited. Moreover, memory for lifestyle-related information as well as medical information provided by the medical professional is often poor and insufficient.

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Objective: To identify implementation determinants of blended periconception lifestyle care, and to evaluate patient satisfaction.

Design: Cross-sectional study.

Setting: The outpatient clinic of the department of Obstetrics and Gynaecology of the Erasmus MC.

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Background: Maternal overweight has a substantial impact on reproductive, maternal, pregnancy, and neonatal outcomes with long-term and transgenerational health consequences. Interventions that aim to optimize periconception maternal lifestyle can improve maternal and fetal health during pregnancy and throughout the life course. However, it remains difficult to change and adopt adequate lifestyle behaviors.

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Article Synopsis
  • * Obesity is linked to absolute and relative folate deficiencies arising from an unbalanced diet, chronic inflammation, and other metabolic issues, which can increase the need for folate beyond dietary intake.
  • * Evidence suggests that higher doses of folic acid supplements may be beneficial for obese women, but the effects of unmetabolized folic acid raise concerns, highlighting the need for more research and personalized counseling on folate status and health.
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Background: Periconception lifestyle behaviors affect maternal, paternal, offspring, and transgenerational health outcomes. Previous research in other target populations has shown that personalized lifestyle interventions, in which face-to-face counseling and eHealth ("blended care") are combined, may effectively target these lifestyle behaviors.

Objective: We aimed to assess the effectiveness of a periconceptional lifestyle intervention on the improvement of specific lifestyle components.

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Background: Worldwide, placenta-related complications contribute to adverse pregnancy outcomes, such as pre-eclampsia, fetal growth restriction and preterm birth, with implications for the future health of mothers and offspring. The placenta develops in the periconception period and forms the interface between mother and embryo/fetus. An unhealthy periconceptional maternal lifestyle, such as smoking, alcohol and under- and over-nutrition, can detrimentally influence placental development and function.

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