Publications by authors named "Melissa Werner"
The effectiveness of a universal adhesive applied in different application modes for the preparation of Class V composite restorations was evaluated both clinically and by quantitative marginal analysis (QMA). In each of the 22 patients, four non-carious cervical lesions (NCCL) were restored with Filtek Supreme XTE (3M). The adhesive Scotchbond Universal (SBU, 3M) was applied in self-etch (SE), selective-enamel-etch (SEE) or etch-and-rinse (ER) modes.
View Article and Find Full Text PDFPurpose: Using a mixed-methods formative evaluation, the purpose of this study was to provide a broad overview of the Alabama eHealth programme set-up and initial patient outcomes. The Alabama eHealth programme uses telemedicine to provide medical care to people living with HIV in rural Alabama. It was led by a community-based organisation, Medical Advocacy and Outreach (MAO), and supported by AIDS United and the Corporation for National Community Service's Social Innovation Fund with matching support from non-federal donors.
View Article and Find Full Text PDFLinkage to HIV medical care and on-going engagement in HIV medical care are vital for ending the HIV epidemic. However, little is known about the cost-utility of HIV linkage, re-engagement and retention (LRC) in care programs. This paper presents the cost-utility analysis of Access to Care, a national HIV LRC program.
View Article and Find Full Text PDFArticle Synopsis
- The 2020 National HIV AIDS Strategy aims for 90% of people living with HIV to stay in care, leading to the creation of the Access to Care (A2C) program focused on linking and retaining vulnerable individuals in high-quality HIV care.
- The study investigated barriers and facilitators in implementing the A2C program through 98 qualitative interviews with staff from participating organizations over 5 years.
- Key barriers included recruitment challenges and resource allocation, while strong partnerships, flexible models, and dedicated staff were identified as significant facilitators, with findings aimed at improving future programs and policies.
Expression of Pitx2 on the left side of the embryo patterns left-right (LR) organs including the dorsal mesentery (DM), whose asymmetric cell behavior directs gut looping. Despite the importance of organ laterality, chromatin-level regulation of Pitx2 remains undefined. Here, we show that genes immediately neighboring Pitx2 in chicken and mouse, including a long noncoding RNA (Pitx2 locus-asymmetric regulated RNA or Playrr), are expressed on the right side and repressed by Pitx2.
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