Publications by authors named "Melissa Trudrung"
Spinal cord injury (SCI) often results in permanent loss of motor and sensory function. After SCI, the blood-spinal cord barrier (BSCB) is disrupted, causing the infiltration of neutrophils and macrophages, which secrete several kinds of cytokines, as well as matrix metalloproteinases (MMPs). MMPs are proteases capable of degrading various extracellular matrix (ECM) proteins, as well as many non-matrix substrates.
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- The study investigates the effectiveness of different suturing techniques (non-absorbable nylon, absorbable vicryl, and fibrin glue) in nerve grafting for rats with sciatic nerve injuries.
- Results show that both vicryl and nylon sutures improved motor function significantly more than controls, with no major differences in nerve recovery overall among the different methods.
- The findings suggest that vicryl sutures are equally effective as nylon sutures for nerve repair, challenging the previous notion that non-absorbable sutures are superior.