Assessing the adaptive role of cannabidiol (CBD) in defense against cannabis aphids.

is known for having unique specialized or secondary metabolites, cannabinoids that are derived from an extension of the terpene pathway in the lineage and includes more than 100 other similar metabolites. Despite the assumption that cannabinoids evolved as novel herbivory defense adaptations, there is limited research addressing the role of cannabinoids in responses to insect herbivores. Here we investigated the role of cannabidiol (CBD), the predominant cannabinoid in hemp, in plant defense against cannabis aphid (), one of the most damaging pests of hemp.