Publications by authors named "Melissa R Tsoi"
Elevated pulmonary vascular resistance (PVR) is a risk factor for mortality after heart transplantation (HT), but whether this association differs for patients with and without left ventricular assist device (LVAD) support before HT is unknown. We analyzed adult first-time HT recipients from the United Network for Organ Sharing (UNOS) registry transplanted between 2010 and 2021. We quantified the association between PVR and the outcomes of 30 day graft failure and 1 year mortality using multivariable logistic regression, stratified by LVAD support status at the time of HT.
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- This review highlights current and investigational therapies for transthyretin amyloidosis (ATTR), focusing on treatments for neuropathic and cardiac symptoms.
- Advances in noninvasive diagnostic techniques have improved early detection, allowing for more effective therapeutic interventions.
- Several new treatments are available or being studied, including methods like tetramer stabilization and gene silencing, which are changing how ATTR is diagnosed and managed.