Publications by authors named "Melissa McCall"

Article Synopsis
  • Marinas contribute to higher levels of copper (Cu) in marine waters, mainly due to antifouling paints used on boat hulls.
  • Washington State is developing legislation to regulate the release of Cu from these paints to protect marine environments.
  • A study conducted in Puget Sound found that enclosed marinas showed significantly higher Cu concentrations than open ones, providing essential data for assessing the impact of future regulations.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the oculocardiac reflex (OCR), a condition causing bradycardia during strabismus surgery, and how various anesthetic techniques impact it, particularly focusing on monitoring methods like BIS and Narcotrend.
  • The research analyzed data from over 2,800 surgical cases, revealing no significant correlation between the percentage of OCR and brain wave patterns, despite varying anesthetic depth between different muscles tested.
  • The study concluded that while certain anesthetic agents and patient age influenced OCR, a direct link between brain wave measurements and the reflex could not be established.
View Article and Find Full Text PDF

In this study, the ability of nanocarriers containing protein transduction domains (PTDs) of various classes to improve cutaneous paclitaxel delivery and efficacy in skin tumor models was evaluated. Microemulsions (MEs) were prepared by mixing a surfactant blend (polyoxyethylene 10 oleoyl ether, ethanol and propylene glycol), monocaprylin, and water. The PTD transportan (ME-T), penetratin (ME-P), or TAT (ME-TAT) was added at a concentration of 1 mM to the plain ME.

View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted to evaluate how five toxic metals from various roofing materials affect stormwater runoff, collecting samples from 14 roofing types during 20 rain events.
  • Most new roofing materials did not show high metal concentrations, but some materials like treated wood shakes and copper roofing showed elevated levels of arsenic, copper, and zinc compared to controls.
  • The research found that the concentration of metals in the runoff can drop over time and is influenced by factors such as the type of material, its age, and weather conditions, suggesting careful consideration when estimating overall metal releases from roofing materials.
View Article and Find Full Text PDF

In this study, we developed cationic microemulsions containing a protein transduction domain (penetratin) for optimizing paclitaxel localization within the skin. Microemulsions were prepared by mixing a surfactant blend (BRIJ:ethanol:propylene glycol 2:1:1, w/w/w) with monocaprylin (oil phase) at 1.3:1 ratio, and adding water at 30% (ME-30), 43% (ME-43), and 50% (ME-50).

View Article and Find Full Text PDF