Publications by authors named "Melissa Marie Kinkaid"
Article Synopsis
- - Microglia play a key role in regulating cerebral blood flow (CBF), particularly during activities like whisker stimulation or ATP injection, affecting both baseline levels and increases in blood flow.
- - Depleting microglia reduces activity-dependent blood flow responses, but the body still responds normally to other stimuli like adenosine, indicating a specific function for microglia in this process.
- - The regulation of CBF by microglia involves the ATP-sensing receptor P2ry12 and the enzyme CD39, which converts extracellular ATP into adenosine, crucial for neurovascular coupling and maintaining healthy blood flow responses.
